Concepedia

Copper-induced Mitochondrial Dysfunction

Copper-Induced Mitochondrial Dysfunction is a pathological condition characterized by impaired mitochondrial function resulting from excessive intracellular copper accumulation, which disrupts electron transport chain activity, increases oxidative stress, and compromises cellular energy production.

265

Publications

20.6K

Citations

1.3K

Authors

443

Institutions

Publications per year

2017–2026

126

Parents

Publications

265

Copper induces cell death by targeting lipoylated TCA cycle proteins

Peter Tsvetkov, Shannon Coy, Boryana Petrova et al. · Science · 2022 · 4.7K citations · Full text

, , +17

Bioavailable copper modulates oxidative phosphorylation and growth of tumors

Seiko Ishida, Pénélope A. Andreux, Carole Poitry‐Yamate et al. · Proceedings of the National Academy of Sciences · 2013 · 418 citations · Full text

, , +17

The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells

Masazumi Nagai, Nha Huu Vo, Luisa Shin Ogawa et al. · Free Radical Biology and Medicine · 2012 · 354 citations

, , +15

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

Liyang Cui, Arvin M. Gouw, Edward L. LaGory et al. · Nature Biotechnology · 2020 · 339 citations · Full text

, , +14

Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A

Wei Gao, Zhao Huang, Jiufei Duan et al. · Molecular Oncology · 2021 · 332 citations · Full text

, , +17

1–5 of 265

Authors

1.3K

  1. ZT
    Zhaoxin Tang

    South China Agricultural University, China

    20 publications · 1K citations

    17

    h-index

  2. JL
    Jianzhao Liao

    South China Agricultural University, China

    16 publications · 862 citations

    14

    h-index

  3. JP
    Jiaqiang Pan

    South China Agricultural University, China

    13 publications · 787 citations

    13

    h-index

  4. JG
    Jianying Guo

    South China Agricultural University, China

    13 publications · 745 citations

    13

    h-index

  5. QH
    Qingyue Han

    South China Agricultural University, China

    14 publications · 787 citations

    13

    h-index

1–5 of 1.3K

Institutions

443

  1. South China Agricultural University

    Guangzhou, China

    17 h-index

    191 publications

    10.2K citations

  2. Northeast Forestry University

    Harbin, China

    11 h-index

    77 publications

    4.4K citations

  3. Jiangxi Agricultural University

    Nanchang, China

    8 h-index

    30 publications

    825 citations

  4. University of Prince Edward Island

    Charlottetown, Canada

    7 h-index

    29 publications

    816 citations

  5. Universidad Nacional Autónoma de México

    Mexico City, Mexico

    7 h-index

    16 publications

    1K citations

  6. Consejo Nacional de Investigaciones Científicas y Técnicas

    Buenos Aires, Argentina

    6 h-index

    17 publications

    1.1K citations

  7. University of Rome Tor Vergata

    Rome, Italy

    6 h-index

    28 publications

    1.2K citations

  8. Guangxi Normal University

    Guilin, China

    6 h-index

    32 publications

    1.4K citations

1–8 of 443

Venues

  1. Aquatic Toxicology

    11 publications · 1.1K citations

    11

    h-index

  2. Ecotoxicology and Environmental Safety

    EES · 11 publications · 623 citations

    11

    h-index

  3. Journal of Inorganic Biochemistry

    11 publications · 447 citations

    11

    h-index

  4. Biological Trace Element Research

    10 publications · 383 citations

    10

    h-index

  5. Chemico-Biological Interactions

    7 publications · 560 citations

    7

    h-index

1–5