Concepedia

Context-specific Substitution Matrices

Context-Specific Substitution Matrices is a type of substitution matrix in bioinformatics that differs from general substitution matrices by incorporating local sequence context information to more accurately model the probability of amino acid or nucleotide substitutions in specific structural or functional environments.

8

Publications

356

Citations

22

Authors

15

Institutions

Publications per year

2017–2026

2

Parents

Publications

8

Context-dependent optimal substitution matrices

Jeffrey M. Koshi, Richard A. Goldstein · Protein Engineering Design and Selection · 1995 · 105 citations

, , +17

The compositional adjustment of amino acid substitution matrices

Yi‐Kuo Yu, John C. Wootton, Stephen F. Altschul · Proceedings of the National Academy of Sciences · 2003 · 94 citations · Full text

, , +12

Improved pairwise alignments of proteins in the Twilight Zone using local structure predictions

Yao-Ming Huang, Christopher Bystroff · Bioinformatics · 2005 · 48 citations · Full text

, , +15

Construction of non-symmetric substitution matrices derived from proteomes with biased amino acid distributions

Olivier Bastien, Sylvaine Roy, Éric Maréchal · Comptes Rendus Biologies · 2005 · 31 citations

, , +9

GPCRtm: An amino acid substitution matrix for the transmembrane region of class A G Protein-Coupled Receptors

Santiago Ríos, Marta Fernández, Gianluigi Caltabiano et al. · BMC Bioinformatics · 2015 · 28 citations · Full text

, , +13

1–5 of 8

Authors

22

  1. RA
    Richard A. Goldstein

    University of Michigan, United States

    2 publications · 119 citations

    2

    h-index

  2. JM
    Jeffrey M. Koshi

    University of Michigan, United States

    2 publications · 119 citations

    2

    h-index

  3. MF
    Marta Fernández

    Hospital Universitario Ramón y Cajal, Spain

    1 publications · 28 citations

    1

    h-index

  4. YH
    Yao-Ming Huang

    Rensselaer Polytechnic Institute, United States

    1 publications · 48 citations

    1

    h-index

  5. JC
    John C. Wootton

    University of Leeds, United Kingdom

    1 publications · 94 citations

    1

    h-index

1–5 of 22

Institutions

15

  1. University of Michigan

    Ann Arbor, United States

    2 h-index

    4 publications

    238 citations

  2. National Institutes of Health

    Bethesda, United States

    1 h-index

    3 publications

    282 citations

  3. National Center for Biotechnology Information

    Bethesda, United States

    1 h-index

    3 publications

    282 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    1 h-index

    2 publications

    62 citations

  5. University of Copenhagen

    Copenhagen, Denmark

    1 h-index

    3 publications

    36 citations

  6. Rensselaer Polytechnic Institute

    Troy, United States

    1 h-index

    2 publications

    96 citations

  7. Novo Nordisk Foundation

    Copenhagen, Denmark

    1 h-index

    1 publications

    12 citations

  8. Jawaharlal Nehru University

    New Delhi, India

    1 h-index

    2 publications

    48 citations

1–8 of 15

Venues

  1. Protein Engineering Design and Selection

    PEDS · 2 publications · 119 citations

    2

    h-index

  2. BMC Bioinformatics

    1 publications · 28 citations

    1

    h-index

  3. Comptes Rendus Biologies

    1 publications · 31 citations

    1

    h-index

  4. 1

    h-index

  5. BMC Genomics

    1 publications · 12 citations

    1

    h-index

1–5