Concepedia

Constraint-based Pathway Reconstruction

Constraint-Based Pathway Reconstruction is a computational method for inferring metabolic or regulatory pathways by systematically applying biochemical, thermodynamic, and physiological constraints to a genome-scale network model to identify feasible steady-state flux distributions.

52

Publications

7.9K

Citations

283

Authors

130

Institutions

Publications per year

2017–2026

13

Parents

Publications

52

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

Jan Schellenberger, Richard Que, Ronan M. T. Fleming et al. · Nature Protocols · 2011 · 1.9K citations · Full text

, , +17

Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0

Laurent Heirendt, Sylvain Arreckx, Thomas Pfau et al. · Nature Protocols · 2019 · 1.4K citations · Full text

, , +12

The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

Radhakrishnan Mahadevan, Christophe H. Schilling · Metabolic Engineering · 2003 · 1.3K citations

, , +12

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox

Scott A. Becker, Adam M. Feist, Monica L. Mo et al. · Nature Protocols · 2007 · 804 citations

, , +17

A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: i JN746 as a cell factory

Juan Nogales, Bernhard Ø. Palsson, Ines Thiele · BMC Systems Biology · 2008 · 272 citations · Full text

, , +16

1–5 of 52

Authors

283

  1. BØ
    Bernhard Ø. Palsson

    University of California San Diego, United States

    12 publications · 5.2K citations

    12

    h-index

  2. IT
    Ines Thiele

    University of Luxembourg, Luxembourg

    9 publications · 4K citations

    9

    h-index

  3. RM
    Ronan M. T. Fleming

    University of Luxembourg, Luxembourg

    6 publications · 3.6K citations

    6

    h-index

  4. AM
    Adam M. Feist

    University of California San Diego, United States

    4 publications · 2.8K citations

    4

    h-index

  5. AB
    Aarash Bordbar

    University of California San Diego, United States

    4 publications · 3.4K citations

    4

    h-index

1–5 of 283

Institutions

130

  1. University of California San Diego

    San Diego, United States

    12 h-index

    57 publications

    35.7K citations

  2. Novo Nordisk Foundation

    Copenhagen, Denmark

    5 h-index

    6 publications

    1.5K citations

  3. Technical University of Denmark

    Kongens Lyngby, Denmark

    5 h-index

    6 publications

    1.5K citations

  4. University of Iceland

    Reykjavik, Iceland

    4 h-index

    9 publications

    4.5K citations

  5. Genomatica (United States)

    San Diego, United States

    3 h-index

    6 publications

    2.9K citations

  6. La Jolla Bioengineering Institute

    San Diego, United States

    3 h-index

    12 publications

    20.2K citations

  7. Ollscoil na Gaillimhe – University of Galway

    Galway, Ireland

    3 h-index

    8 publications

    471 citations

  8. Wageningen University & Research

    Wageningen, The Netherlands

    2 h-index

    7 publications

    151 citations

1–8 of 130

Venues

  1. BMC Systems Biology

    5 publications · 781 citations

    5

    h-index

  2. Bioinformatics

    5 publications · 104 citations

    5

    h-index

  3. Nature Protocols

    3 publications · 4.1K citations

    3

    h-index

  4. Metabolic Engineering

    3 publications · 1.3K citations

    3

    h-index

  5. Molecular BioSystems

    2 publications · 98 citations

    2

    h-index

1–5