Concepedia

Conformational Substates

Conformational Substates is a theoretical construct in structural biology representing distinct, transient three-dimensional arrangements of a biomolecule that preexist in equilibrium and are selectively stabilized by binding partners in the conformational selection model.

288

Publications

20.4K

Citations

1K

Authors

347

Institutions

Publications per year

2017–2026

40

Parents

Publications

288

The Energy Landscapes and Motions of Proteins

Hans Frauenfelder, Stephen G. Sligar, Peter G. Wolynes · Science · 1991 · 3.2K citations

, , +17

The Dynamic Energy Landscape of Dihydrofolate Reductase Catalysis

David D. Boehr, Dan McElheny, H. Jane Dyson et al. · Science · 2006 · 961 citations

, , +17

Solvent viscosity and protein dynamics

D. Beece, L. Eisenstein, Hans Frauenfelder et al. · Biochemistry · 1980 · 665 citations

, , +17

The Role of Solvent Viscosity in the Dynamics of Protein Conformational Changes

Anjum Ansari, Colleen M. Jones, Eric R. Henry et al. · Science · 1992 · 559 citations

, , +15

Bulk-solvent and hydration-shell fluctuations, similar to α- and β-fluctuations in glasses, control protein motions and functions

Paul W. Fenimore, Hans Frauenfelder, Benjamin H. McMahon et al. · Proceedings of the National Academy of Sciences · 2004 · 518 citations

, , +16

1–5 of 288

Authors

1K

  1. HF
    Hans Frauenfelder

    University of Illinois Urbana-Champaign, United States

    9 publications · 5.3K citations

    9

    h-index

  2. FP
    F. Parak

    Technical University of Munich, Germany

    7 publications · 563 citations

    7

    h-index

  3. WL
    Wayne L. Hubbell

    University of California, Los Angeles, United States

    7 publications · 575 citations

    7

    h-index

  4. RW
    Roland Winter

    TU Dortmund University, Germany

    6 publications · 206 citations

    6

    h-index

  5. AC
    Antonio Cupane

    University of Palermo, Italy

    6 publications · 111 citations

    6

    h-index

1–5 of 1K

Institutions

347

  1. University of Illinois Urbana-Champaign

    Urbana, United States

    15 h-index

    63 publications

    14.7K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    40 publications

    2.1K citations

  3. Technical University of Munich

    Munich, Germany

    10 h-index

    24 publications

    1.2K citations

  4. Stanford University

    Stanford, United States

    9 h-index

    33 publications

    2.6K citations

  5. University of Palermo

    Palermo, Italy

    8 h-index

    24 publications

    741 citations

  6. University of California, Los Angeles

    Los Angeles, United States

    8 h-index

    20 publications

    1.8K citations

  7. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    23 publications

    1.2K citations

  8. Doheny Eye Institute

    Los Angeles, United States

    7 h-index

    19 publications

    1.6K citations

1–8 of 347

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 32 publications · 3.2K citations

    28

    h-index

  2. Biochemistry

    35 publications · 2.2K citations

    23

    h-index

  3. Journal of the American Chemical Society

    JACS · 28 publications · 1.6K citations

    22

    h-index

  4. The Journal of Physical Chemistry B

    24 publications · 719 citations

    17

    h-index

  5. The Journal of Chemical Physics

    14 publications · 766 citations

    14

    h-index

1–5