Concepedia

Conditional Allele Generation

Conditional Allele Generation is a genetic engineering method that enables the creation of alleles whose expression or function can be spatially or temporally controlled in response to specific external or internal stimuli, thereby allowing precise investigation of gene function within the context of forward chemical genetics.

84

Publications

4.8K

Citations

478

Authors

160

Institutions

Publications per year

2017–2026

10

Parents

Publications

84

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in <i>Drosophila</i>

Scott J. Gratz, Fiona P. Ukken, C. Dustin Rubinstein et al. · Genetics · 2014 · 1.1K citations · Full text

, , +17

Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types

Jacqueline A. Walisser, Edward Glover, Kalyan Pande et al. · Proceedings of the National Academy of Sciences · 2005 · 234 citations · Full text

, , +17

Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation

Martin O. Bergö, Patricia Ambroziak, Cria Gregory et al. · Molecular and Cellular Biology · 2002 · 145 citations · Full text

, , +14

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

Vinod Pant, Shunbin Xiong, Tomoo Iwakuma et al. · Proceedings of the National Academy of Sciences · 2011 · 134 citations

, , +13

Dual RMCE for efficient re-engineering of mouse mutant alleles

Marco Osterwalder, Antonella Galli, Barry P. Rosen et al. · Nature Methods · 2010 · 133 citations

, , +16

1–5 of 84

Authors

478

  1. MD
    Matthew D. Breyer

    Vanderbilt University, United States

    3 publications · 129 citations

    3

    h-index

  2. YM
    Yuji Mishina

    University of Michigan, United States

    3 publications · 70 citations

    3

    h-index

  3. TG
    Thomas Gridley

    Jackson Laboratory, United States

    3 publications · 166 citations

    3

    h-index

  4. VK
    Vesa Kaartinen

    Children's Hospital of Los Angeles, United States

    3 publications · 116 citations

    3

    h-index

  5. MA
    Mark A. Magnuson

    Vanderbilt University, United States

    2 publications · 118 citations

    2

    h-index

1–5 of 478

Institutions

160

  1. Baylor College of Medicine

    Houston, United States

    5 h-index

    24 publications

    1.4K citations

  2. Zero to Three

    Washington, United States

    5 h-index

    9 publications

    376 citations

  3. National Institute of Environmental Health Sciences

    Durham, United States

    5 h-index

    16 publications

    621 citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    4 h-index

    14 publications

    1K citations

  5. Vanderbilt University Medical Center

    Nashville, United States

    4 h-index

    16 publications

    891 citations

  6. Jackson Laboratory

    Bar Harbor, United States

    4 h-index

    12 publications

    531 citations

  7. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    30 publications

    8.9K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    14 publications

    346 citations

1–8 of 160

Venues

  1. genesis

    49 publications · 1.9K citations

    28

    h-index

  2. PLoS ONE

    6 publications · 252 citations

    6

    h-index

  3. Nucleic Acids Research

    3 publications · 105 citations

    3

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 447 citations

    3

    h-index

  5. Transgenic Research

    3 publications · 78 citations

    3

    h-index

1–5