Concepedia

Concentration-dependent Killing Interactions

Concentration-Dependent Killing Interactions is a pharmacodynamic interaction in antimicrobial therapy wherein the magnitude and rate of microbial killing are primarily determined by the peak concentration of the antimicrobial agent relative to the pathogen's minimum inhibitory concentration, distinguishing it from time-dependent killing mechanisms that rely on duration of exposure.

40

Publications

2.1K

Citations

167

Authors

73

Institutions

Publications per year

2017–2026

5

Parents

Publications

40

Aminoglycosides: a practical review.

Luis S. Gonzalez, J P E Spencer · PubMed · 1998 · 216 citations

, , +14

Lactobacilli Inactivate Chlamydia trachomatis through Lactic Acid but Not H2O2

Zheng Gong, Yesmin Luna, Ping Yu et al. · PLoS ONE · 2014 · 191 citations · Full text

, , +15

Synergism between aminoglycosides and cephalosporins with antipseudomonal activity: interaction index and killing curve method

Hans O. Hallander, K. Dornbusch, Lena Gezelius et al. · Antimicrobial Agents and Chemotherapy · 1982 · 161 citations · Full text

, , +16

Terpinen-4-ol is the Most Active Ingredient of Tea Tree Oil to Kill<i>Demodex</i>Mites

Sean Tighe, Yingying Gao, Scheffer C.G. Tseng · Translational Vision Science & Technology · 2013 · 130 citations · Full text

, , +13

Interactions between Antibiotics and Human Neutrophils in the Killing of Staphylococci

Richard K. Root, Raúl Istúriz, Abdolghader Molavi et al. · Journal of Clinical Investigation · 1981 · 104 citations · Full text

, , +13

1–5 of 40

Authors

167

  1. CR
    Christian Rodríguez Rodrígues

    Fundación Ciencias Exactas y Naturales, Argentina

    1 publications · 50 citations

    1

    h-index

  2. MA
    Mohamed Afnan

    Hamilton General Hospital, Canada

    1 publications · 24 citations

    1

    h-index

  3. LE
    Lennart E. Nilsson

    Linköping University, Sweden

    1 publications · 12 citations

    1

    h-index

  4. KD
    K. Dornbusch

    Karolinska University Hospital, Sweden

    1 publications · 161 citations

    1

    h-index

  5. LS
    Luis S. Gonzalez

    Conemaugh Health System, United States

    1 publications · 216 citations

    1

    h-index

1–5 of 167

Institutions

73

  1. Fujian Medical University

    Fuzhou, China

    1 h-index

    1 publications

    130 citations

  2. Second Affiliated Hospital of Fujian Medical University

    Quanzhou, China

    1 h-index

    1 publications

    130 citations

  3. Gesundheitsamt

    Frankfurt am Main, Germany

    1 h-index

    7 publications

    84 citations

  4. UCLA Medical Center

    Santa Monica, United States

    1 h-index

    5 publications

    215 citations

  5. Aligarh Muslim University

    Aligarh, India

    1 h-index

    3 publications

    264 citations

  6. University of Wisconsin–Madison

    Madison, United States

    1 h-index

    5 publications

    235 citations

  7. National Measurement Laboratory

    Canberra, Australia

    1 h-index

    5 publications

    520 citations

  8. National Institutes of Health

    Bethesda, United States

    1 h-index

    2 publications

    28 citations

1–8 of 73

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 8 publications · 442 citations

    8

    h-index

  2. Journal of Antimicrobial Chemotherapy

    JAC · 4 publications · 128 citations

    4

    h-index

  3. The Journal of Infectious Diseases

    JID · 2 publications · 129 citations

    2

    h-index

  4. PubMed

    Repository · 2 publications · 235 citations

    2

    h-index

  5. PLoS ONE

    2 publications · 259 citations

    2

    h-index

1–5