Concepedia

Computational Strain Design

Computational Strain Design is a systematic methodology within systems metabolic engineering that employs computational models and algorithms to predict genetic and regulatory modifications enabling the optimization of microbial strains for desired biochemical production.

68

Publications

3.8K

Citations

273

Authors

105

Institutions

Publications per year

2017–2026

38

Parents

Publications

68

In silico design and adaptive evolution of <i>Escherichia coli</i> for production of lactic acid

Stephen S. Fong, Anthony P. Burgard, Christopher D. Herring et al. · Biotechnology and Bioengineering · 2005 · 366 citations

, , +17

A machine learning Automated Recommendation Tool for synthetic biology

Nature Communications · 2020 · 261 citations · Full text

, , +11

OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains

Joonhoon Kim, Jennifer L. Reed · BMC Systems Biology · 2010 · 217 citations · Full text

, , +17

Growth-coupled overproduction is feasible for almost all metabolites in five major production organisms

Axel von Kamp, Steffen Klamt · Nature Communications · 2017 · 164 citations · Full text

, , +17

Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in <i>Escherichia coli</i> Aided by Machine Learning

Paul H. Opgenorth, Zak Costello, Takuya Okada et al. · ACS Synthetic Biology · 2019 · 162 citations · Full text

, , +17

1–5 of 68

Authors

273

  1. SK
    Steffen Klamt

    Max Planck Institute for Dynamics of Complex Technical Systems, Germany

    7 publications · 420 citations

    7

    h-index

  2. CD
    Costas D. Maranas

    Pennsylvania State University, United States

    6 publications · 662 citations

    6

    h-index

  3. AC
    Anupam Chowdhury

    Pennsylvania State University, United States

    4 publications · 269 citations

    4

    h-index

  4. RM
    Radhakrishnan Mahadevan

    University of Toronto, Canada

    4 publications · 240 citations

    4

    h-index

  5. AV
    Axel von Kamp

    Max Planck Institute for Dynamics of Complex Technical Systems, Germany

    4 publications · 274 citations

    4

    h-index

1–5 of 273

Institutions

105

  1. Novo Nordisk Foundation

    Copenhagen, Denmark

    7 h-index

    13 publications

    626 citations

  2. Max Planck Institute for Dynamics of Complex Technical Systems

    Magdeburg, Germany

    7 h-index

    17 publications

    949 citations

  3. Pennsylvania State University

    State College, United States

    6 h-index

    14 publications

    1.5K citations

  4. University of California San Diego

    San Diego, United States

    6 h-index

    15 publications

    1.9K citations

  5. Technical University of Denmark

    Kongens Lyngby, Denmark

    5 h-index

    11 publications

    563 citations

  6. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    8 publications

    1.2K citations

  7. University of Toronto

    Toronto, Canada

    4 h-index

    9 publications

    671 citations

  8. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    25 publications

    3.4K citations

1–8 of 105

Venues

  1. Bioinformatics

    8 publications · 218 citations

    8

    h-index

  2. Microbial Cell Factories

    5 publications · 316 citations

    5

    h-index

  3. Biotechnology and Bioengineering

    5 publications · 520 citations

    5

    h-index

  4. PLoS Computational Biology

    5 publications · 308 citations

    5

    h-index

  5. Metabolic Engineering

    4 publications · 285 citations

    4

    h-index

1–5