Concepedia

Computational Developability Prediction

Computational Developability Prediction is a scholarly methodological framework that systematically employs computational models and algorithms to quantitatively assess the likelihood of successful development and manufacturability of therapeutic candidates, particularly biopharmaceuticals, by predicting physicochemical and biological properties indicative of developability.

14

Publications

1.1K

Citations

86

Authors

27

Institutions

Publications per year

2017–2026

11

Parents

Publications

14

Five computational developability guidelines for therapeutic antibody profiling

Matthew I. J. Raybould, Claire Marks, Konrad Krawczyk et al. · Proceedings of the National Academy of Sciences · 2019 · 368 citations · Full text

, , +17

Developability Index: A Rapid In Silico Tool for the Screening of Antibody Aggregation Propensity

Timothy M. Lauer, Neeraj J. Agrawal, Naresh Chennamsetty et al. · Journal of Pharmaceutical Sciences · 2011 · 215 citations

, , +15

Neuro-genetic prediction of software development effort

K.K. Shukla · Information and Software Technology · 2000 · 97 citations

, , +14

<i>In-silico</i> prediction of concentration-dependent viscosity curves for monoclonal antibody solutions

Dheeraj S. Tomar, Li Li, Matthew P. Broulidakis et al. · mAbs · 2017 · 90 citations · Full text

, , +17

Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools

Lu Shan, Neil Mody, Pietro Sormani et al. · Molecular Pharmaceutics · 2018 · 69 citations

, , +17

1–5 of 14

Authors

86

  1. CM
    Charlotte M. Deane

    University of Oxford, United Kingdom

    3 publications · 432 citations

    3

    h-index

  2. MI
    Matthew I. J. Raybould

    University of Oxford, United Kingdom

    3 publications · 432 citations

    3

    h-index

  3. KK
    Konrad Krawczyk

    University of Oxford, United Kingdom

    2 publications · 394 citations

    2

    h-index

  4. PZ
    Pavol Zlatoidský

    State Institute for Drug Control, Slovakia

    1 publications · 34 citations

    1

    h-index

  5. RA
    Rahmad Akbar

    University of Oslo, Norway

    1 publications · 26 citations

    1

    h-index

1–5 of 86

Institutions

27

  1. University of Oxford

    Oxford, United Kingdom

    3 h-index

    12 publications

    2.1K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    5 publications

    205 citations

  3. UCB Pharma (United Kingdom)

    Slough, United Kingdom

    2 h-index

    5 publications

    416 citations

  4. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    1 h-index

    2 publications

    68 citations

  5. Roche Pharma AG (Germany)

    Grenzach-Wyhlen, Germany

    1 h-index

    1 publications

    368 citations

  6. AstraZeneca (Sweden)

    Södertälje, Sweden

    1 h-index

    6 publications

    204 citations

  7. Max Planck Institute of Biochemistry

    Martinsried, Germany

    1 h-index

    1 publications

    34 citations

  8. Oxford Research Group

    London, United Kingdom

    1 h-index

    2 publications

    50 citations

1–8 of 27

Venues

  1. mAbs

    3 publications · 143 citations

    3

    h-index

  2. Communications Biology

    2 publications · 65 citations

    2

    h-index

  3. Molecular Pharmaceutics

    1 publications · 69 citations

    1

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 28 citations

    1

    h-index

  5. Nature Communications

    1 publications · 34 citations

    1

    h-index

1–5