Concepedia

Complementarity-determining Region 3

Complementarity-Determining Region 3 is a hypervariable structural loop within the antigen-binding site of immunoglobulin molecules that uniquely determines the specificity of B-cell receptor recognition through its highly diverse nucleotide sequence formed by V(D)J recombination.

453

Publications

29K

Citations

3K

Authors

778

Institutions

Publications per year

2017–2026

107

Variants

Cdr3

Parents

Publications

453

Replacing the complementarity-determining regions in a human antibody with those from a mouse

Peter Jones, Paul H. Dear, Jefferson Foote et al. · Nature · 1986 · 1.4K citations

, , +13

Diversity in the CDR3 Region of VH Is Sufficient for Most Antibody Specificities

Mark M. Davis · Immunity · 2000 · 804 citations · Full text

, , +16

CDR3 length in antigen-specific immune receptors.

Edwin P. Rock, Peter R. Sibbald, Mark M. Davis et al. · The Journal of Experimental Medicine · 1994 · 513 citations · Full text

, , +17

Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity

Hitoshi Suzuki, Run Fan, Zhixin Zhang et al. · Journal of Clinical Investigation · 2009 · 453 citations · Full text

, , +17

Antigen-Specific Development of Primary and Memory T Cells in Vivo

Michael G. McHeyzer‐Williams, Mark M. Davis · Science · 1995 · 434 citations

, , +17

1–5 of 453

Authors

3K

  1. PK
    Philippe Kourilsky

    Institut Pasteur, France

    6 publications · 298 citations

    6

    h-index

  2. HN
    Haruki Nakamura

    The University of Osaka, Japan

    6 publications · 473 citations

    6

    h-index

  3. SG
    Stanley G. Nathenson

    Albert Einstein College of Medicine, United States

    5 publications · 307 citations

    5

    h-index

  4. SB
    Sophie Brouard

    Inserm, France

    4 publications · 180 citations

    4

    h-index

  5. BI
    Boris I. Chobrutskiy

    University of South Florida, United States

    4 publications · 81 citations

    4

    h-index

1–5 of 3K

Institutions

778

  1. National Institutes of Health

    Bethesda, United States

    16 h-index

    50 publications

    2.3K citations

  2. Scripps Research Institute

    San Diego, United States

    16 h-index

    119 publications

    7.7K citations

  3. Inserm

    Paris, France

    13 h-index

    74 publications

    4.6K citations

  4. Harvard University

    Cambridge, United States

    12 h-index

    59 publications

    2.6K citations

  5. Institut Pasteur

    Paris, France

    9 h-index

    30 publications

    2.6K citations

  6. Cornell University

    Ithaca, United States

    9 h-index

    30 publications

    3.7K citations

  7. Stanford University

    Stanford, United States

    9 h-index

    35 publications

    8K citations

  8. University of Oxford

    Oxford, United Kingdom

    8 h-index

    29 publications

    2.1K citations

1–8 of 778

Venues

  1. The Journal of Immunology

    JI · 88 publications · 5.1K citations

    43

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 30 publications · 2.6K citations

    27

    h-index

  3. Journal of Biological Chemistry

    JBC · 13 publications · 1.5K citations

    13

    h-index

  4. PubMed

    Repository · 15 publications · 561 citations

    12

    h-index

  5. European Journal of Immunology

    EJI · 13 publications · 507 citations

    11

    h-index

1–5