Concepedia

Complement-mediated Sperm Damage

Complement-Mediated Sperm Damage is a pathophysiological mechanism in reproductive immunology wherein the activation of the complement system on sperm surfaces leads to membrane attack complex formation, resulting in loss of sperm integrity, motility, and fertilizing capacity.

16

Publications

504

Citations

43

Authors

13

Institutions

Publications per year

2017–2026

0

Parents

Publications

16

Membrane attack complex (MAC)-mediated damage to spermatozoa: protection of the cells by the presence on their membranes of MAC inhibitory proteins.

Isabelle Rooney, Alun Davies, B. Paul Morgan · PubMed · 1992 · 72 citations

, , +17

Activation of human complement by IgG antisperm antibody and the demonstration of C3 and C5b-9-mediated immune injury to human sperm

Osmond J. D’Cruz, Gilbert G. Haas, B L Wang et al. · The Journal of Immunology · 1991 · 59 citations · Full text

, , +16

THE EFFECTS OF SERUM ON SPERMATOZOA

M. C. Chang · The Journal of General Physiology · 1947 · 48 citations · Full text

, , +6

CHARACTERIZATION OF A NATURAL ANTIBODY IN NORMAL GUINEA-PIG SERUM REACTING WITH HOMOLOGOUS SPERMATOZOA

Martin H. Johnson · Reproduction · 1968 · 46 citations

, , +12

Expression of the complement regulatory protein CD59 on human spermatozoa: Characterization and role in gametic interaction

Patrick Fénichel, F Cervoni, Peter Hofmann et al. · Molecular Reproduction and Development · 1994 · 46 citations

, , +17

1–5 of 16

Authors

43

  1. GG
    Gilbert G. Haas

    University of Oklahoma Health Sciences Center, United States

    5 publications · 175 citations

    5

    h-index

  2. OJ
    Osmond J. D’Cruz

    Parker Hughes Cancer Center, United States

    5 publications · 175 citations

    5

    h-index

  3. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    2 publications · 86 citations

    2

    h-index

  4. PH
    Peter Hofmann

    Charité - Universitätsmedizin Berlin, Germany

    1 publications · 46 citations

    1

    h-index

  5. BL
    B L Wang

    Rosalind Franklin University of Medicine and Science, United States

    1 publications · 59 citations

    1

    h-index

1–5 of 43

Institutions

13

  1. University of Oklahoma Health Sciences Center

    Oklahoma City, United States

    5 h-index

    13 publications

    504 citations

  2. Isfahan Fertility and Infertility Center

    Isfahan, Iran

    1 h-index

    1 publications

    11 citations

  3. State University of New York

    Albany, United States

    1 h-index

    5 publications

    80 citations

  4. Isfahan University of Medical Sciences

    Isfahan, Iran

    1 h-index

    4 publications

    44 citations

  5. Stony Brook University

    Stony Brook, United States

    1 h-index

    5 publications

    80 citations

  6. Cardiff University

    Cardiff, United Kingdom

    1 h-index

    3 publications

    42 citations

  7. University of Virginia

    Charlottesville, United States

    1 h-index

    2 publications

    42 citations

  8. University of Turku

    Turku, Finland

    1 h-index

    3 publications

    39 citations

1–8 of 13

Venues

  1. Biology of Reproduction

    5 publications · 126 citations

    5

    h-index

  2. PubMed

    Repository · 2 publications · 88 citations

    2

    h-index

  3. Journal of Reproductive Immunology

    2 publications · 30 citations

    2

    h-index

  4. Journal of Assisted Reproduction and Genetics

    JARG · 1 publications · 11 citations

    1

    h-index

  5. Fertility and Sterility

    1 publications · 37 citations

    1

    h-index

1–5