Complement-mediated Ocular Injury

Complement-Mediated Ocular Injury is a pathological process in which aberrant or excessive activation of the complement system leads to tissue damage and inflammation specifically within ocular structures, distinguishing it from other forms of ocular injury by its immunological mechanism centered on complement cascade dysregulation.

169

Publications

9.8K

Citations

850

Authors

273

Institutions

Publications per year

2017–2026

Parents

Immunopathology Of The Eye

Publications

169

Complement Activation and Inflammatory Processes in Drusen Formation and Age Related Macular Degeneration

Lincoln V. Johnson, William P. Leitner, Michelle K. Staples et al. · Experimental Eye Research · 2001 · 615 citations

Medicine, Immunology, Ophthalmology +17

Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration

Andrew P. Voigt, Kelly Mulfaul, Nathaniel K. Mullin et al. · Proceedings of the National Academy of Sciences · 2019 · 399 citations · Full text

Life Sciences, Cell Biology, Ophthalmology +17

Systemic Complement Inhibition with Eculizumab for Geographic Atrophy in Age-Related Macular Degeneration

Zohar Yehoshua, Carlos Alexandre de Amorim Garcia Filho, Renata Portella Nunes et al. · Ophthalmology · 2013 · 296 citations

Medicine, Immunology, Ophthalmology +16

Y402H Polymorphism of Complement Factor H Affects Binding Affinity to C-Reactive Protein

Matti Laine, Hanna Jarva, Sanna Seitsonen et al. · The Journal of Immunology · 2007 · 243 citations · Full text

Medicine, Genetics, Ophthalmology +17

Oxidative Stress and the Regulation of Complement Activation in Human Glaucoma

Gülgün Tezel, Xiangjun Yang, Cheng Luo et al. · Investigative Ophthalmology & Visual Science · 2010 · 222 citations · Full text

Medicine, Biochemistry, Ophthalmology +17

1–5 of 169

Authors

850

BR
Bärbel Rohrer
Medical University of South Carolina, United States
12 publications · 596 citations
12
h-index
PJ
Purushottam Jha
University of Arkansas for Medical Sciences, United States
8 publications · 471 citations
8
h-index
PS
Puran S. Bora
University of Arkansas for Medical Sciences, United States
8 publications · 471 citations
8
h-index
KK
Kannan Kunchithapautham
Medical University of South Carolina, United States
7 publications · 609 citations
7
h-index
BC
Beth Coughlin
Medical University of South Carolina, United States
7 publications · 464 citations
7
h-index

1–5 of 850

Institutions

273

1–8 of 273

Venues

Investigative Ophthalmology & Visual Science
IOVS · 29 publications · 1.8K citations
22
h-index
PubMed
Repository · 19 publications · 676 citations
14
h-index
Experimental Eye Research
8 publications · 1.1K citations
8
h-index
The Journal of Immunology
JI · 7 publications · 729 citations
7
h-index
Current Eye Research
5 publications · 117 citations
5
h-index

1–5