Concepedia

Complement-mediated Host Defense

Complement-Mediated Host Defense is a biological defense mechanism that functions through the activation of the complement system to selectively identify, opsonize, and eliminate pathogens while preserving host tissues via precise regulatory control.

1.6K

Publications

80.6K

Citations

5.4K

Authors

1.2K

Institutions

Publications per year

2017–2026

147

Parents

Publications

1.6K

P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1

J. Alexandra Rowe, Joann M. Moulds, Chris Newbold et al. · Nature · 1997 · 588 citations

, , +16

Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury

Kenneth R. McCurry, David L. Kooyman, Cristobal G. Alvarado et al. · Nature Medicine · 1995 · 540 citations

, , +14

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

Michael R. Wessels, Peter Butko, Minghe Ma et al. · Proceedings of the National Academy of Sciences · 1995 · 505 citations

, , +17

Natural hemolytic and bactericidal activities of sea bream Sparus aurata serum are effected by the alternative complement pathway

J. Oriol Sunyer, Lluís Tort · Veterinary Immunology and Immunopathology · 1995 · 460 citations

, , +12

Antiphagocytic activity of streptococcal M protein: selective binding of complement control protein factor H.

Rolf D. Horstmann, H J Sievertsen, J Knobloch et al. · Proceedings of the National Academy of Sciences · 1988 · 452 citations · Full text

, , +17

1–5 of 1.6K

Authors

5.4K

  1. PF
    Peter F. Zipfel

    Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI), Germany

    43 publications · 3.7K citations

    34

    h-index

  2. SR
    Sanjay Ram

    University of Massachusetts Chan Medical School, United States

    36 publications · 2.1K citations

    27

    h-index

  3. AM
    Anna M. Blom

    Lund University, Sweden

    32 publications · 2K citations

    27

    h-index

  4. SM
    Seppo Meri

    University of Helsinki, Finland

    30 publications · 2.7K citations

    26

    h-index

  5. CS
    Christine Skerka

    Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI), Germany

    22 publications · 2K citations

    21

    h-index

1–5 of 5.4K

Institutions

1.2K

  1. Lund University

    Lund, Sweden

    35 h-index

    170 publications

    10.9K citations

  2. Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)

    Jena, Germany

    34 h-index

    120 publications

    11.8K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    33 h-index

    142 publications

    12.9K citations

  4. University of Helsinki

    Helsinki, Finland

    31 h-index

    142 publications

    13.2K citations

  5. National Institutes of Health

    Bethesda, United States

    30 h-index

    134 publications

    13.7K citations

  6. University of Pennsylvania

    Philadelphia, United States

    28 h-index

    95 publications

    7.9K citations

  7. University of Massachusetts Chan Medical School

    Worcester, United States

    26 h-index

    116 publications

    6.7K citations

  8. Harvard University

    Cambridge, United States

    26 h-index

    112 publications

    8.2K citations

1–8 of 1.2K

Venues

  1. The Journal of Immunology

    JI · 153 publications · 10.1K citations

    64

    h-index

  2. Infection and Immunity

    IAI · 198 publications · 11.2K citations

    61

    h-index

  3. PubMed

    Repository · 102 publications · 3.5K citations

    34

    h-index

  4. The Journal of Infectious Diseases

    JID · 54 publications · 2.4K citations

    32

    h-index

  5. Journal of Biological Chemistry

    JBC · 39 publications · 2.6K citations

    29

    h-index

1–5