Concepedia

Complement-mediated Histamine Release

Complement-Mediated Histamine Release is a biological mechanism in which histamine is liberated from mast cells or basophils through the activation of the complement system, specifically via anaphylatoxins such as C3a and C5a binding to their respective receptors.

127

Publications

7.4K

Citations

286

Authors

92

Institutions

Publications per year

2017–2026

3

Parents

Publications

127

STUDIES ON THE MECHANISMS OF HYPERSENSITIVITY PHENOMENA

Lawrence M. Lichtenstein, Abraham G. Osler · The Journal of Experimental Medicine · 1964 · 662 citations · Full text

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Release of histamine from rat mast cells by the complement peptides C3a and C5a.

Alice Johnson, Tony E. Hugli, Hans J. Müller‐Eberhard · PubMed · 1975 · 294 citations

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Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin. Polypeptide sequence determination and assignment of the oligosaccharide attachment site in C5a.

H.N. Fernández, Tony E. Hugli · Journal of Biological Chemistry · 1978 · 252 citations · Full text

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Roles of histamine, complement and xanthine oxidase in thermal injury of skin.

H. P. Friedl, Gerd O. Till, O. Trentz et al. · PubMed · 1989 · 238 citations

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Complement Peptides C3a- and C5a-Induced Mediator Release from Dissociated Human Skin Mast Cells

Suhad El-Lati, Martin K. Church, Clemens A. Dahinden · Journal of Investigative Dermatology · 1994 · 222 citations

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1–5 of 127

Authors

286

  1. KF
    K. Frank Austen

    Harvard University, United States

    8 publications · 478 citations

    8

    h-index

  2. WA
    W. Alexander Van Hook

    University of Tennessee at Knoxville, United States

    8 publications · 467 citations

    8

    h-index

  3. AG
    Abraham G. Osler

    Johns Hopkins University, United States

    8 publications · 909 citations

    8

    h-index

  4. RP
    Reuben P. Siraganian

    National Institute of Dental and Craniofacial Research, United States

    7 publications · 433 citations

    7

    h-index

  5. DO
    David O. Thueson

    The University of Texas Medical Branch at Galveston, United States

    7 publications · 376 citations

    7

    h-index

1–5 of 286

Institutions

92

  1. The University of Texas Medical Branch at Galveston

    Galveston, United States

    9 h-index

    39 publications

    1.9K citations

  2. Johns Hopkins University

    Baltimore, United States

    8 h-index

    18 publications

    2.4K citations

  3. Harvard University

    Cambridge, United States

    6 h-index

    25 publications

    665 citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    6 h-index

    12 publications

    1.7K citations

  5. Scripps Health

    San Diego, United States

    5 h-index

    14 publications

    1.2K citations

  6. Massachusetts General Hospital

    Boston, United States

    5 h-index

    14 publications

    580 citations

  7. National Institute of Dental and Craniofacial Research

    Bethesda, United States

    5 h-index

    13 publications

    555 citations

  8. National Institutes of Health

    Bethesda, United States

    5 h-index

    13 publications

    555 citations

1–8 of 92

Venues

  1. PubMed

    Repository · 26 publications · 1.7K citations

    22

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  2. The Journal of Immunology

    JI · 26 publications · 1.3K citations

    19

    h-index

  3. The Journal of Experimental Medicine

    11 publications · 1.4K citations

    11

    h-index

  4. Journal of Allergy and Clinical Immunology

    5 publications · 441 citations

    5

    h-index

  5. 4

    h-index

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