Concepedia

Compartmentalized Self-replication

Compartmentalized Self-Replication is a self-replication paradigm in which autonomous replicating units are physically or functionally isolated within discrete compartments, enabling parallel evolution and selection while minimizing cross-contamination and resource interference.

15

Publications

1.8K

Citations

61

Authors

35

Institutions

Publications per year

2017–2026

8

Parents

Publications

15

Nature of the Scrapie Agent: Self-replication and Scrapie

J. S. Griffith · Nature · 1967 · 1.1K citations

, , +5

Directed evolution of polymerase function by compartmentalized self-replication

Farid J. Ghadessy, Jennifer L. Ong, Philipp Holliger · Proceedings of the National Academy of Sciences · 2001 · 392 citations · Full text

, , +14

Autonomous model protocell division driven by molecular replication

James W. Taylor, Seyed Ali Eghtesadi, Laurie J. Points et al. · Nature Communications · 2017 · 59 citations · Full text

, , +13

Importance of compartment formation for a self-encoding system

Tomoaki Matsuura, Muneyoshi Yamaguchi, Elizabeth P. Ko-Mitamura et al. · Proceedings of the National Academy of Sciences · 2002 · 35 citations

, , +11

Compartmentalized self-replication under fast PCR cycling conditions yields Taq DNA polymerase mutants with increased DNA-binding affinity and blood resistance

Bahram Arezi, Nancy McKinney, Connie Hansen et al. · Frontiers in Microbiology · 2014 · 31 citations · Full text

, , +14

1–5 of 15

Authors

61

  1. PH
    Philipp Holliger

    MRC Laboratory of Molecular Biology, United Kingdom

    2 publications · 418 citations

    2

    h-index

  2. FJ
    Farid J. Ghadessy

    Agency for Science, Technology and Research, Singapore

    2 publications · 418 citations

    2

    h-index

  3. TY
    Tetsuya Yomo

    The University of Osaka, Japan

    2 publications · 56 citations

    2

    h-index

  4. NI
    Norikazu Ichihashi

    The University of Osaka, Japan

    2 publications · 46 citations

    2

    h-index

  5. TL
    Tianbo Liu

    University of Akron, United States

    1 publications · 59 citations

    1

    h-index

1–5 of 61

Institutions

35

  1. The University of Osaka

    Osaka, Japan

    2 h-index

    8 publications

    252 citations

  2. Japan Science and Technology Agency

    Tokyo, Japan

    2 h-index

    2 publications

    46 citations

  3. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    2 h-index

    5 publications

    1.2K citations

  4. The University of Tokyo

    Tokyo, Japan

    2 h-index

    8 publications

    260 citations

  5. Universidade Federal do Rio de Janeiro

    Rio de Janeiro, Brazil

    1 h-index

    1 publications

    16 citations

  6. TU Dortmund University

    Dortmund, Germany

    1 h-index

    2 publications

    48 citations

  7. Gulliver

    Paris, France

    1 h-index

    2 publications

    32 citations

  8. Bedford College

    Bedford, United Kingdom

    1 h-index

    1 publications

    1.1K citations

1–8 of 35

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 427 citations

    2

    h-index

  2. Life

    2 publications · 27 citations

    2

    h-index

  3. Nature Communications

    2 publications · 83 citations

    2

    h-index

  4. Chemical Communications

    ChemComm · 1 publications · 25 citations

    1

    h-index

  5. Mechanisms of Ageing and Development

    1 publications · 10 citations

    1

    h-index

1–5