Concepedia

Compartmental Parameter Estimation

Compartmental Parameter Estimation is a mathematical inference procedure within pharmacokinetic modeling that determines the rate constants and volume of distribution characterizing drug movement between conceptual physiological compartments by fitting observed concentration-time data to a predefined compartmental structure.

98

Publications

4.4K

Citations

283

Authors

140

Institutions

Publications per year

2017–2026

7

Parents

Publications

98

Comparison of Methods for Analysis of Clinical [ <sup>11</sup> C]Raclopride Studies

Adriaan A. Lammertsma, C. J. Bench, S.P. Hume et al. · Journal of Cerebral Blood Flow & Metabolism · 1996 · 461 citations

, , +15

Shortcomings in Pharmacokinetic Analysis by Conceiving the Body to Exhibit Properties of a Single Compartment

Sidney Riegelman, J.C.K. Loo, Malcolm Rowland · Journal of Pharmaceutical Sciences · 1968 · 381 citations

, , +16

Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

Vincent J. Cunningham, Eugenii A. Rabiner, Mark Slifstein et al. · Journal of Cerebral Blood Flow & Metabolism · 2009 · 272 citations · Full text

, , +13

A Strategy for Removing the Bias in the Graphical Analysis Method

Jean Logan, Joanna S. Fowler, Nora D. Volkow et al. · Journal of Cerebral Blood Flow & Metabolism · 2001 · 175 citations · Full text

, , +16

A Comparative Survey of Automated Parameter-Search Methods for Compartmental Neural Models

Michael Vanier, James M. Bower · Journal of Computational Neuroscience · 1999 · 171 citations

, , +16

1–5 of 98

Authors

283

  1. JJ
    Joseph J. DiStefano

    University of California, Los Angeles, United States

    3 publications · 58 citations

    3

    h-index

  2. VS
    Volker Schmid

    University of Basel, Switzerland

    3 publications · 36 citations

    3

    h-index

  3. KG
    K.R. Godfrey

    University of Warwick, United Kingdom

    3 publications · 48 citations

    3

    h-index

  4. CC
    Claudio Cobelli

    University of Padua, Italy

    3 publications · 53 citations

    3

    h-index

  5. EM
    Elliot M. Landaw

    University of California, Los Angeles, United States

    3 publications · 58 citations

    3

    h-index

1–5 of 283

Institutions

140

  1. Columbia University

    New York, United States

    5 h-index

    9 publications

    861 citations

  2. Ludwig-Maximilians-Universität München

    Munich, Germany

    4 h-index

    7 publications

    88 citations

  3. University of Padua

    Padua, Italy

    3 h-index

    6 publications

    106 citations

  4. California Institute of Technology

    Pasadena, United States

    3 h-index

    6 publications

    688 citations

  5. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    9 publications

    174 citations

  6. Lancaster University

    Lancaster, United Kingdom

    2 h-index

    2 publications

    51 citations

  7. Oregon State University

    Corvallis, United States

    2 h-index

    3 publications

    64 citations

  8. University of Warwick

    Coventry, United Kingdom

    2 h-index

    5 publications

    85 citations

1–8 of 140

Venues

  1. Mathematical Biosciences

    9 publications · 191 citations

    9

    h-index

  2. IEEE Transactions on Biomedical Engineering

    7 publications · 207 citations

    7

    h-index

  3. Journal of Cerebral Blood Flow & Metabolism

    6 publications · 1.1K citations

    6

    h-index

  4. Journal of Pharmaceutical Sciences

    5 publications · 479 citations

    5

    h-index

  5. Biometrics

    4 publications · 186 citations

    4

    h-index

1–5