Concepedia

Comparative Somatic Mutation Analysis

Comparative Somatic Mutation Analysis is a computational genomics approach that systematically identifies, contrasts, and interprets patterns of somatically acquired genetic alterations across species, tissues, or tumor types to elucidate evolutionary, functional, or etiological distinctions in cancer development and progression.

44

Publications

2.9K

Citations

421

Authors

147

Institutions

Publications per year

2017–2026

18

Parents

Publications

44

Somatic mutation rates scale with lifespan across mammals

Alex Cagan, Adrian Baez‐Ortega, Natalia Brzozowska et al. · Nature · 2022 · 472 citations · Full text

, , +16

The mutational landscape of human somatic and germline cells

Luiza Moore, Alex Cagan, Tim Coorens et al. · Nature · 2021 · 389 citations

, , +15

Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations.

Mika Tirkkonen, Oskar T. Johannsson, Bjarni A. Agnarsson et al. · PubMed · 1997 · 355 citations

, , +16

Integrative and Comparative Genomic Analysis of Lung Squamous Cell Carcinomas in East Asian Patients

Young-Wook Kim, Peter S. Hammerman, Jaegil Kim et al. · Journal of Clinical Oncology · 2013 · 204 citations · Full text

, , +16

Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations

Jiaying Deng, Hu Chen, Daizhan Zhou et al. · Nature Communications · 2017 · 131 citations · Full text

, , +17

1–5 of 44

Authors

421

  1. YH
    Yvette Hooks

    Wellcome Sanger Institute, United Kingdom

    5 publications · 988 citations

    5

    h-index

  2. MA
    Mathijs A. Sanders

    Erasmus MC, Netherlands

    5 publications · 988 citations

    5

    h-index

  3. TB
    Timothy Butler

    Wellcome Sanger Institute, United Kingdom

    5 publications · 988 citations

    5

    h-index

  4. AC
    Alex Cagan

    Wellcome Sanger Institute, United Kingdom

    5 publications · 988 citations

    5

    h-index

  5. TC
    Tim Coorens

    Wellcome Sanger Institute, United Kingdom

    5 publications · 988 citations

    5

    h-index

1–5 of 421

Institutions

147

  1. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    19 publications

    4.7K citations

  2. Heidelberg University

    Heidelberg, Germany

    4 h-index

    12 publications

    1.7K citations

  3. Wellcome Sanger Institute

    Cambridge, United Kingdom

    4 h-index

    82 publications

    19.9K citations

  4. Johns Hopkins University

    Baltimore, United States

    3 h-index

    7 publications

    704 citations

  5. Newcastle University

    Newcastle upon Tyne, United Kingdom

    3 h-index

    3 publications

    513 citations

  6. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    2 h-index

    8 publications

    91 citations

  7. Baylor College of Medicine

    Houston, United States

    2 h-index

    4 publications

    410 citations

  8. Heidelberg Institute for Stem Cell Technology and Experimental Medicine

    Heidelberg, Germany

    2 h-index

    6 publications

    1.6K citations

1–8 of 147

Venues

  1. Human Mutation

    4 publications · 176 citations

    4

    h-index

  2. PubMed

    Repository · 4 publications · 440 citations

    4

    h-index

  3. Genome Research

    GR · 2 publications · 93 citations

    2

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 114 citations

    2

    h-index

  5. Nature

    2 publications · 861 citations

    2

    h-index

1–5