Concepedia

Combinatorial Library Space

Combinatorial Library Space is a structured chemical space representation that encompasses the complete set of synthetically accessible compounds derivable from a defined set of building blocks and reaction rules, distinguishing it from other chemical spaces by its explicit enumeration of combinatorially generated molecular architectures.

63

Publications

4.3K

Citations

216

Authors

77

Institutions

Publications per year

2017–2026

19

Parents

Publications

63

Property Distributions:  Differences between Drugs, Natural Products, and Molecules from Combinatorial Chemistry

Miklós Fehér, Jonathan M. Schmidt · Journal of Chemical Information and Computer Sciences · 2002 · 921 citations

, , +16

Machine learning-assisted directed protein evolution with combinatorial libraries

Zachary Wu, S. B. Jennifer Kan, Russell D. Lewis et al. · Proceedings of the National Academy of Sciences · 2019 · 619 citations · Full text

, , +17

Stochastic Voyages into Uncharted Chemical Space Produce a Representative Library of All Possible Drug-Like Compounds

Aaron M. Virshup, Julia Contreras‐García, Peter Wipf et al. · Journal of the American Chemical Society · 2013 · 327 citations · Full text

, , +17

Pharmaceutical Matters

Andrew Barry · Theory Culture & Society · 2005 · 192 citations

, , +11

A Close-up Look at the Chemical Space of Commercially Available Building Blocks for Medicinal Chemistry

Yuliana Zabolotna, Dmitriy M. Volochnyuk, Sergey V. Ryabukhin et al. · Journal of Chemical Information and Modeling · 2021 · 106 citations

, , +17

1–5 of 63

Authors

216

  1. DH
    Dragos Horvath

    Université de Strasbourg, France

    4 publications · 169 citations

    4

    h-index

  2. JM
    John M. Barnard

    Barnardo's, United Kingdom

    3 publications · 88 citations

    3

    h-index

  3. RK
    Raphael Klein

    University of Bergen, Norway

    3 publications · 115 citations

    3

    h-index

  4. GM
    Gilles Marcou

    Université de Strasbourg, France

    3 publications · 129 citations

    3

    h-index

  5. AV
    Alexandre Varnek

    Université de Strasbourg, France

    3 publications · 129 citations

    3

    h-index

1–5 of 216

Institutions

77

  1. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    21 publications

    840 citations

  2. Université de Strasbourg

    Strasbourg, France

    4 h-index

    13 publications

    532 citations

  3. Universität Hamburg

    Hamburg, Germany

    3 h-index

    7 publications

    281 citations

  4. Simulations Plus (United States)

    Lancaster, United States

    2 h-index

    4 publications

    239 citations

  5. Boehringer Ingelheim (Germany)

    Ingelheim, Germany

    2 h-index

    5 publications

    308 citations

  6. Barnardo's

    London, United Kingdom

    2 h-index

    5 publications

    131 citations

  7. University of Minnesota

    Minneapolis, United States

    2 h-index

    5 publications

    196 citations

  8. Torrey Pines Institute For Molecular Studies

    San Diego, United States

    2 h-index

    3 publications

    44 citations

1–8 of 77

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 8 publications · 398 citations

    8

    h-index

  2. 6

    h-index

  3. Journal of Molecular Graphics and Modelling

    3 publications · 94 citations

    3

    h-index

  4. Journal of Combinatorial Chemistry

    3 publications · 115 citations

    3

    h-index

  5. Journal of Medicinal Chemistry

    3 publications · 242 citations

    3

    h-index

1–5