Concepedia

Raphael Klein

RK

8

Publications

301

Citations

8

H-Index

2001

Active since

Affiliations

University of Bergen(Current)

Universität Hamburg

Johannes Gutenberg University Mainz

Raphael Klein is an author at University of Bergen specializing in drug discovery, chemistry, and medicine.

Top concepts

MedicineChemistryDrug DiscoveryEngineeringBiochemistryPharmacologyMolecular DesignNatural SciencesDesignHealth

Publications per year

2001–2023

8

Publications

8

Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors

Paul Beroza, James J. Crawford, Oleg Ganichkin et al. · Nature Communications · 2022 · 102 citations · Full text

Maximum Common Substructure Searching in Combinatorial Make-on-Demand Compound Spaces

Robert Schmidt, Raphael Klein, Matthias Rarey · Journal of Chemical Information and Modeling · 2021 · 56 citations

Mathematical Programming, Combinatorial Chemistry, Engineering +19

Magnet for the Needle in Haystack: “Crystal Structure First” Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces

Janis Müller, Raphael Klein, Olga O. Tarkhanova et al. · Journal of Medicinal Chemistry · 2022 · 42 citations · Full text

Relevance of the Trillion-Sized Chemical Space “eXplore” as a Source for Drug Discovery

Alexander Neumann, Lester Marrison, Raphael Klein · ACS Medicinal Chemistry Letters · 2023 · 40 citations · Full text

Drug Target, Hit Identification, Virtual Product Molecules +17

Grupe, A. et al. In silico mapping of complex disease-related traits in mice. Science 292, 1915-1918

Jonathan Usuka, Raphael Klein, Russell Higuchi et al. · 2001 · 25 citations

Silico Mapping, Science 292, Disease Mechanism +10

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