Concepedia

Combinatorial Diversity Design

Combinatorial Diversity Design is a methodological framework in antibody library construction that systematically generates extensive sequence variation by recombining diverse gene segments or mutagenic elements to maximize the coverage of antigen-binding specificities within a synthetic or semi-synthetic library.

8

Publications

307

Citations

49

Authors

17

Institutions

Publications per year

2017–2026

1

Parents

Publications

8

Diversity-oriented synthesis as a tool for identifying new modulators of mitosis

Brett M. Ibbeson, Luca Laraia, Esther Alza et al. · Nature Communications · 2014 · 82 citations · Full text

, , +14

Combinatorial library design for diversity, cost efficiency, and drug-like character

Robert D. Brown, Moises Hassan, Marvin Waldman · Journal of Molecular Graphics and Modelling · 2000 · 71 citations

, , +16

Advances in diversity profiling and combinatorial series design

Dimitris K. Agrafiotis, James C. Myslik, F. Raymond Salemme · Molecular Diversity · 1998 · 47 citations

, , +8

Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p

Volker Seibert, Corinna Prohl, Ida Schoultz et al. · BMC Biochemistry · 2002 · 42 citations · Full text

, , +13

Programming Cells by Multicopy Chromosomal Integration Using CRISPR-Associated Transposases

Yiwen Zhang, Jiawei Yang, Siqi Yang et al. · The CRISPR Journal · 2021 · 37 citations

, , +17

1–5 of 8

Authors

49

  1. GJ
    Grahame J. McKenzie

    University of Cambridge, United Kingdom

    1 publications · 82 citations

    1

    h-index

  2. SS
    S. Stanley Young

    National Institute of Statistical Sciences, United States

    1 publications · 13 citations

    1

    h-index

  3. JY
    Jiawei Yang

    Shanghai Institutes for Biological Sciences, China

    1 publications · 37 citations

    1

    h-index

  4. SY
    Siqi Yang

    University of Chinese Academy of Sciences, China

    2 publications · 74 citations

    1

    h-index

  5. AR
    Ashok R. Venkitaraman

    University of Cambridge, United Kingdom

    1 publications · 82 citations

    1

    h-index

1–5 of 49

Institutions

17

  1. Boston University

    Boston, United States

    2 h-index

    9 publications

    350 citations

  2. University of Waterloo

    Waterloo, Canada

    1 h-index

    1 publications

    13 citations

  3. University of Cambridge

    Cambridge, United Kingdom

    1 h-index

    8 publications

    656 citations

  4. Emory University

    Atlanta, United States

    1 h-index

    1 publications

    82 citations

  5. University of Southern California

    Los Angeles, United States

    1 h-index

    2 publications

    74 citations

  6. Medical Research Council

    London, United Kingdom

    1 h-index

    2 publications

    164 citations

  7. Dana-Farber/Harvard Cancer Center

    Boston, United States

    1 h-index

    1 publications

    42 citations

  8. Simulations Plus (United States)

    Lancaster, United States

    1 h-index

    3 publications

    213 citations

1–8 of 17

Venues

  1. Molecular Diversity

    1 publications · 14 citations

    1

    h-index

  2. Nature Communications

    1 publications · 82 citations

    1

    h-index

  3. BMC Biochemistry

    1 publications · 42 citations

    1

    h-index

  4. PLoS ONE

    1 publications · 29 citations

    1

    h-index

  5. Journal of Molecular Graphics and Modelling

    1 publications · 71 citations

    1

    h-index

1–5