Concepedia

Cofactor Substrate Coupling

Cofactor Substrate Coupling is a biochemical engineering strategy that integrates the kinetics and thermodynamics of cofactor-dependent enzymatic reactions with substrate utilization to enhance metabolic flux and product yield by synchronizing cofactor regeneration with substrate conversion.

14

Publications

674

Citations

59

Authors

24

Institutions

Publications per year

2017–2026

3

Parents

Publications

14

General ligands in affinity chromatography. Cofactor–substrate elution of enzymes bound to the immobilized nucleotides adenosine 5′-monophosphate and nicotinamide–adenine dinucleotide

Klaus Mosbach, H. Guilford, Rolf Ohlsson et al. · Biochemical Journal · 1972 · 203 citations · Full text

, , +16

Evidence for a dipyrromethane cofactor at the catalytic site of <i>E. coli</i> porphobilinogen deaminase

Peter M. Jordan, Martin J. Warren · FEBS Letters · 1987 · 143 citations · Full text

, , +16

Laccase-catalysed synthesis of coupling products of phenolic substrates in different reactors

R. Pilz, Elke Hammer, Frieder Schauer et al. · Applied Microbiology and Biotechnology · 2003 · 54 citations

, , +16

Modelling of two enzyme reactions in a linked cofactor recycle system for chiral lactone synthesis

Matthew Hogan, John M. Woodley · Chemical Engineering Science · 2000 · 37 citations

, , +16

Non‐natural Cofactor and Formate‐Driven Reductive Carboxylation of Pyruvate

Xiaojia Guo, Yuxue Liu, Qian Wang et al. · Angewandte Chemie International Edition · 2019 · 37 citations

, , +17

1–5 of 14

Authors

59

  1. LW
    Linda W. Jennings

    Baylor University Medical Center, United States

    1 publications · 10 citations

    1

    h-index

  2. VB
    Vicente Bernal

    Universidad de Murcia, Spain

    1 publications · 12 citations

    1

    h-index

  3. YX
    Youyu Xie

    East China University of Science and Technology, China

    1 publications · 28 citations

    1

    h-index

  4. CW
    C. W. Shuster

    Case Western Reserve University, United States

    1 publications · 18 citations

    1

    h-index

  5. VD
    Viviana De Luca

    University of Florence, Italy

    1 publications · 24 citations

    1

    h-index

1–5 of 59

Institutions

24

  1. University of Chinese Academy of Sciences

    Beijing, China

    2 h-index

    9 publications

    305 citations

  2. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    17 publications

    589 citations

  3. Czech Academy of Sciences, Institute of Biotechnology

    Prague, Czechia

    1 h-index

    7 publications

    196 citations

  4. University of Florence

    Florence, Italy

    1 h-index

    1 publications

    24 citations

  5. University of Rostock

    Rostock, Germany

    1 h-index

    2 publications

    108 citations

  6. Universidad de Murcia

    Murcia, Spain

    1 h-index

    5 publications

    60 citations

  7. Institute of Technology Carlow

    Carlow, Ireland

    1 h-index

    4 publications

    40 citations

  8. Institute of Biosciences and Bioresources

    Bari, Italy

    1 h-index

    4 publications

    96 citations

1–8 of 24

Venues

  1. Biochemical Journal

    1 publications · 203 citations

    1

    h-index

  2. Chemical Engineering Science

    1 publications · 37 citations

    1

    h-index

  3. Bioscience Biotechnology and Biochemistry

    1 publications · 22 citations

    1

    h-index

  4. Analytical Biochemistry

    1 publications · 10 citations

    1

    h-index

  5. Icarus

    1 publications · 33 citations

    1

    h-index

1–5