Youyu Xie

Mechanism‐Guided Computational Design of ω‐Transaminase by Reprograming of High‐Energy‐Barrier Steps

Lin Yang, Kaiyue Zhang, Meng Xu et al. · Angewandte Chemie International Edition · 2022 · 40 citations

Engineering, Chemistry, Molecular Biology +17

Efficient Asymmetric Synthesis of Ethyl (<i>S</i>)-4-Chloro-3-hydroxybutyrate Using Alcohol Dehydrogenase <i>Sm</i>ADH31 with High Tolerance of Substrate and Product in a Monophasic Aqueous System

Zeyu Yang, Wenjie Ye, Youyu Xie et al. · Organic Process Research & Development · 2020 · 35 citations

Life Sciences, Biochemistry, Biotechnology +13

Efficient asymmetric synthesis of chiral alcohols using high 2-propanol tolerance alcohol dehydrogenase <i>Sm</i>ADH2 <i>via</i> an environmentally friendly TBCR system

Zeyu Yang, Hengwei Fu, Wenjie Ye et al. · Catalysis Science & Technology · 2019 · 28 citations

Engineering, Biochemistry, Biotechnology +13

Efficient Biocatalytic Synthesis of (<i>R</i>)-2-Chloro-1-(3,4-difluorophenyl)ethanol by the Short-Chain Dehydrogenase <i>Pp</i>KR8 from <i>Paraburkholderia phymatum</i> STM815

Ling He, Wenjie Ye, Youyu Xie et al. · Organic Process Research & Development · 2022 · 14 citations

Life Sciences, Biochemistry, Biotechnology +13

Engineering the large pocket of an (<i>S</i>)-selective transaminase for asymmetric synthesis of (<i>S</i>)-1-amino-1-phenylpropane

Youyu Xie, Feng Xu, Lin Yang et al. · Catalysis Science & Technology · 2021 · 12 citations

Natural Sciences, Biochemistry, Chemistry +8