Concepedia

Cofactor Binding Site Design

Cofactor Binding Site Design is a computational or structural biology method that specifies the rational engineering of protein active sites to selectively accommodate and stabilize specific cofactors through precise spatial and chemical complementarity.

9

Publications

497

Citations

44

Authors

21

Institutions

Publications per year

2017–2026

0

Parents

Publications

9

Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme

Osamu Nureki, Kazunori Watanabe, Shuya Fukai et al. · Structure · 2004 · 142 citations · Full text

, , +17

Antibody remodeling: a general solution to the design of a metal-coordination site in an antibody binding pocket.

Victoria A. Roberts, Brent L. Iverson, Sheila A. Iverson et al. · Proceedings of the National Academy of Sciences · 1990 · 115 citations

, , +17

A Cluster of Positively Charged Amino Acids in the C4BP α-Chain Is Crucial for C4b Binding and Factor I Cofactor Function

Anna M. Blom, Joanna H. Webb, Bruno O. Villoutreix et al. · Journal of Biological Chemistry · 1999 · 108 citations · Full text

, , +13

Efficient Synthesis ofS-Adenosyl-L-Homocysteine Natural Product Analogues and Their Use to Elucidate the Structural Determinant for Cofactor Binding of the DNA Methyltransferase M·HhaI

Marc Pignot, Goran Pljevaljčić, Elmar G. Weinhold · European Journal of Organic Chemistry · 2000 · 45 citations

, , +13

mRNA:guanine-N 7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

Janusz M. Bujnicki, Marcin Feder, Monika Radlińska et al. · BMC Bioinformatics · 2001 · 29 citations · Full text

, , +17

1–5 of 9

Authors

44

  1. JM
    Janusz M. Bujnicki

    International Institute of Molecular and Cell Biology, Poland

    1 publications · 29 citations

    1

    h-index

  2. SA
    Sheila A. Iverson

    Scripps Clinic, United States

    1 publications · 115 citations

    1

    h-index

  3. LP
    Lise Pedersen

    University of Copenhagen, Denmark

    1 publications · 13 citations

    1

    h-index

  4. HH
    Hiroyuki Hori

    Ehime University, Japan

    1 publications · 142 citations

    1

    h-index

  5. RA
    Richard A. Lerner

    Scripps Research Institute, United States

    1 publications · 115 citations

    1

    h-index

1–5 of 44

Institutions

21

  1. Mahidol University

    Bangkok, Thailand

    1 h-index

    2 publications

    36 citations

  2. Ehime University

    Matsuyama, Japan

    1 h-index

    4 publications

    568 citations

  3. Malmö University

    Malmo, Sweden

    1 h-index

    4 publications

    432 citations

  4. University of Kansas

    Lawrence, United States

    1 h-index

    7 publications

    84 citations

  5. Max Planck Society

    Munich, Germany

    1 h-index

    3 publications

    135 citations

  6. International Institute of Molecular and Cell Biology

    Warsaw, Poland

    1 h-index

    3 publications

    87 citations

  7. BioInfoBank Institute

    Poznań, Poland

    1 h-index

    1 publications

    29 citations

  8. RIKEN

    Wako, Japan

    1 h-index

    1 publications

    142 citations

1–8 of 21

Venues

  1. Nucleosides Nucleotides & Nucleic Acids

    1 publications · 12 citations

    1

    h-index

  2. BMC Bioinformatics

    1 publications · 29 citations

    1

    h-index

  3. Journal of Molecular Graphics and Modelling

    1 publications · 15 citations

    1

    h-index

  4. Structure

    1 publications · 142 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 115 citations

    1

    h-index

1–5