Concepedia

Codon Selection At Initiation

Codon Selection At Initiation is a molecular biology mechanism that specifies the selection of a particular start codon on an mRNA transcript by the small ribosomal subunit during the initiation phase of translation, distinguishing it from general codon recognition processes by its dependence on initiation factors, ribosomal positioning, and context-specific nucleotide signals that determine translational start site fidelity.

40

Publications

2.9K

Citations

176

Authors

81

Institutions

Publications per year

2017–2026

4

Parents

Publications

40

Selection of AUG initiation codons differs in plants and animals.

H Lütcke, Kuan‐Chih Chow, F.S. Mickel et al. · The EMBO Journal · 1987 · 1K citations · Full text

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Codon optimization of human factor VIII cDNAs leads to high-level expression

Natalie J Ward, Suzanne M. K. Buckley, Simon N. Waddington et al. · Blood · 2010 · 181 citations

, , +15

Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo

Yuen-Nei Cheung, David Maag, Sarah F. Mitchell et al. · Genes & Development · 2007 · 169 citations · Full text

, , +17

CUG initiation codon used for the synthesis of a cell surface antigen coded by the murine leukemia virus

Anne‐Catherine Prats, Gérard de Billy, Piao Wang et al. · Journal of Molecular Biology · 1989 · 151 citations

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Domains of initiator tRNA and initiation codon crucial for initiator tRNA selection by Escherichia coli IF3.

Dieter Hartz, J P Binkley, Tamy Hollingsworth et al. · Genes & Development · 1990 · 132 citations · Full text

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1–5 of 40

Authors

176

  1. AG
    Alan G. Hinnebusch

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    4 publications · 376 citations

    4

    h-index

  2. JR
    Jon R. Lorsch

    Johns Hopkins University, United States

    4 publications · 376 citations

    4

    h-index

  3. TV
    Tatyana V. Pestova

    SUNY Downstate Health Sciences University, United States

    3 publications · 321 citations

    3

    h-index

  4. CA
    Christie A. Fekete

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    2 publications · 293 citations

    2

    h-index

  5. MA
    Mikkel A. Algire

    AbbVie (United States), United States

    2 publications · 293 citations

    2

    h-index

1–5 of 176

Institutions

81

  1. National Institutes of Health

    Bethesda, United States

    5 h-index

    16 publications

    1.3K citations

  2. Johns Hopkins University

    Baltimore, United States

    4 h-index

    15 publications

    1.7K citations

  3. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    4 h-index

    10 publications

    1.1K citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    4 h-index

    15 publications

    1.7K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    6 publications

    187 citations

  6. Whitehead Institute for Biomedical Research

    Cambridge, United States

    2 h-index

    9 publications

    258 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    8 publications

    676 citations

  8. Harvard University

    Cambridge, United States

    2 h-index

    11 publications

    1K citations

1–8 of 81

Venues

  1. Nucleic Acids Research

    7 publications · 297 citations

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  2. Genes & Development

    3 publications · 332 citations

    3

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  3. Biosystems

    2 publications · 30 citations

    2

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  4. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 76 citations

    2

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  5. PLoS ONE

    2 publications · 27 citations

    2

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