Concepedia

Coated Pit Formation

Coated Pit Formation is a cellular process in which a specialized region of the plasma membrane invaginates to form a clathrin-coated depression, initiated by the recruitment and assembly of endocytic adaptor proteins that link cargo receptors to the underlying clathrin lattice, thereby distinguishing it from non-coated endocytic mechanisms by its reliance on clathrin-adaptor protein complexes for membrane curvature and vesicle nucleation.

202

Publications

28.6K

Citations

721

Authors

244

Institutions

Publications per year

2017–2026

14

Parents

Publications

202

Coated pits, coated vesicles, and receptor-mediated endocytosis

Joseph L. Goldstein, Richard G.W. Anderson, Michael S. Brown · Nature · 1979 · 2.1K citations

, , +12

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation.

L H Wang, Karen G. Rothberg, Richard G.W. Anderson · The Journal of Cell Biology · 1993 · 1.2K citations · Full text

, , +17

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

Wei J. Chen, J L Goldstein, Mark S. Brown · Journal of Biological Chemistry · 1990 · 944 citations · Full text

, , +16

Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.

John E. Heuser, Richard G.W. Anderson · The Journal of Cell Biology · 1989 · 932 citations · Full text

, , +13

Endocytosis by Random Initiation and Stabilization of Clathrin-Coated Pits

Marcelo Ehrlich, Werner Boll, Antoine M. van Oijen et al. · Cell · 2004 · 882 citations · Full text

, , +11

1–5 of 202

Authors

721

  1. RG
    Richard G.W. Anderson

    The University of Texas Southwestern Medical Center, United States

    15 publications · 5.8K citations

    15

    h-index

  2. TK
    Tomas Kirchhausen

    Harvard University, United States

    14 publications · 2.5K citations

    14

    h-index

  3. SL
    Sandra L. Schmid

    Scripps Research Institute, United States

    10 publications · 1.5K citations

    10

    h-index

  4. ES
    Elizabeth Smythe

    University of Sheffield, United Kingdom

    6 publications · 785 citations

    6

    h-index

  5. FM
    Frances M. Brodsky

    University of California, San Francisco, United States

    5 publications · 338 citations

    5

    h-index

1–5 of 721

Institutions

244

  1. Harvard University

    Cambridge, United States

    18 h-index

    61 publications

    11.9K citations

  2. The University of Texas Southwestern Medical Center

    Dallas, United States

    18 h-index

    66 publications

    13.8K citations

  3. National Institutes of Health

    Bethesda, United States

    12 h-index

    44 publications

    4.1K citations

  4. Yale University

    New Haven, United States

    11 h-index

    44 publications

    9.3K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    34 publications

    7.6K citations

  6. Scripps Research Institute

    San Diego, United States

    8 h-index

    24 publications

    3.6K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    25 publications

    5.9K citations

  8. University of California, San Francisco

    San Francisco, United States

    7 h-index

    33 publications

    6.9K citations

1–8 of 244

Venues

  1. The Journal of Cell Biology

    JCB · 35 publications · 6.5K citations

    33

    h-index

  2. Journal of Biological Chemistry

    JBC · 25 publications · 3.7K citations

    23

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 17 publications · 2.9K citations

    17

    h-index

  4. Cell

    9 publications · 3.1K citations

    9

    h-index

  5. Journal of Cell Science

    9 publications · 849 citations

    9

    h-index

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