Concepedia

Clinical Dose Optimization

Clinical Dose Optimization is a pharmacological methodology that systematically determines the optimal drug dosage regimen to maximize therapeutic efficacy while minimizing toxicity within the context of an individual patient’s clinical profile and the drug’s therapeutic index.

201

Publications

10.3K

Citations

1.3K

Authors

526

Institutions

Publications per year

2017–2026

79

Parents

Publications

201

AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011

Christoph Hiemke, Pierre Baumann, N. Bergemann et al. · Pharmacopsychiatry · 2011 · 865 citations · Full text

, , +16

Lapatinib Plus Paclitaxel Versus Paclitaxel Alone in the Second-Line Treatment of <i>HER2</i>-Amplified Advanced Gastric Cancer in Asian Populations: TyTAN—A Randomized, Phase III Study

Taroh Satoh, Rui‐Hua Xu, Hyun Cheol Chung et al. · Journal of Clinical Oncology · 2014 · 624 citations · Full text

, , +15

Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy.

Varsha Gandhi, Elihu H. Estey, M Keating et al. · Journal of Clinical Oncology · 1993 · 335 citations

, , +17

Regorafenib dose-optimisation in patients with refractory metastatic colorectal cancer (ReDOS): a randomised, multicentre, open-label, phase 2 study

Tanios Bekaii‐Saab, Fang‐Shu Ou, Daniel H. Ahn et al. · The Lancet Oncology · 2019 · 284 citations · Full text

, , +12

The Drug-Dosing Conundrum in Oncology — When Less Is More

Mirat Shah, Atiqur Rahman, Marc R. Theoret et al. · New England Journal of Medicine · 2021 · 278 citations

, , +17

1–5 of 201

Authors

1.3K

  1. JH
    Jos H. Beijnen

    The Netherlands Cancer Institute, Netherlands

    5 publications · 292 citations

    5

    h-index

  2. HM
    Hagop M. Kantarjian

    The University of Texas MD Anderson Cancer Center, United States

    5 publications · 140 citations

    5

    h-index

  3. SB
    Sharon B. Wigal

    University of California, Irvine, United States

    4 publications · 89 citations

    4

    h-index

  4. AH
    Andreas Hochhaus

    Jena University Hospital, Germany

    4 publications · 102 citations

    4

    h-index

  5. TG
    Tawanda Gumbo

    Baylor University Medical Center, United States

    4 publications · 169 citations

    4

    h-index

1–5 of 1.3K

Institutions

526

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    10 h-index

    22 publications

    955 citations

  2. Memorial Sloan Kettering Cancer Center

    New York, United States

    7 h-index

    39 publications

    1.9K citations

  3. Heidelberg University

    Heidelberg, Germany

    7 h-index

    26 publications

    686 citations

  4. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    6 h-index

    27 publications

    1.1K citations

  5. University of California, San Francisco

    San Francisco, United States

    6 h-index

    17 publications

    504 citations

  6. Pfizer (United States)

    New York, United States

    6 h-index

    39 publications

    820 citations

  7. Inserm

    Paris, France

    5 h-index

    16 publications

    1.1K citations

  8. Utrecht University

    Utrecht, The Netherlands

    5 h-index

    11 publications

    597 citations

1–8 of 526

Venues

  1. PubMed

    Repository · 14 publications · 874 citations

    12

    h-index

  2. Journal of Clinical Oncology

    9 publications · 1.2K citations

    9

    h-index

  3. Clinical Cancer Research

    6 publications · 529 citations

    6

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 5 publications · 271 citations

    5

    h-index

  5. Cancer Chemotherapy and Pharmacology

    5 publications · 117 citations

    5

    h-index

1–5