Concepedia

Cleavage Factor Function

Cleavage Factor Function is a molecular mechanism in the genus of transcriptional regulation processes that specifically mediates the endonucleolytic cleavage of nascent RNA transcripts to facilitate transcription termination by enabling the recruitment and activation of termination factors at specific genomic loci.

89

Publications

6.4K

Citations

368

Authors

132

Institutions

Publications per year

2017–2026

16

Parents

Publications

89

Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length

Georges Martín, Andreas Gruber, Walter Keller et al. · Cell Reports · 2012 · 381 citations · Full text

, , +17

Transcript cleavage factors from E. coli

Sergei Borukhov, V Sagitov, Alex Goldfarb · Cell · 1993 · 369 citations

, , +8

A Mechanism for the Regulation of Pre-mRNA 3′ Processing by Human Cleavage Factor Im

Kirk Brown, Gregory M. Gilmartin · Molecular Cell · 2003 · 246 citations · Full text

, , +14

Complex Protein Interactions within the Human Polyadenylation Machinery Identify a Novel Component

Yoshio Takagaki, James L. Manley · Molecular and Cellular Biology · 2000 · 244 citations

, , +17

Four factors are required for 3'-end cleavage of pre-mRNAs.

Y Takagaki, L C Ryner, James L. Manley · Genes & Development · 1989 · 223 citations · Full text

, , +15

1–5 of 89

Authors

368

  1. CM
    Claire Moore

    Tufts University, United States

    10 publications · 601 citations

    10

    h-index

  2. WK
    Walter Keller

    University of Graz, Austria

    6 publications · 1.1K citations

    6

    h-index

  3. JL
    James L. Manley

    Columbia University, United States

    5 publications · 796 citations

    5

    h-index

  4. SB
    Sergei Borukhov

    Rowan University, United States

    4 publications · 450 citations

    4

    h-index

  5. MS
    Martine Simonelig

    Institut de Génétique Humaine, France

    3 publications · 71 citations

    3

    h-index

1–5 of 368

Institutions

132

  1. Tufts University

    Medford, United States

    11 h-index

    31 publications

    1.7K citations

  2. University of Basel

    Basel, Switzerland

    8 h-index

    31 publications

    4.4K citations

  3. Columbia University

    New York, United States

    7 h-index

    22 publications

    2.8K citations

  4. State University of New York

    Albany, United States

    3 h-index

    4 publications

    114 citations

  5. Imperial College London

    London, United Kingdom

    3 h-index

    6 publications

    149 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    6 publications

    627 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    8 publications

    420 citations

  8. Kyoto University

    Kyoto, Japan

    3 h-index

    5 publications

    325 citations

1–8 of 132

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 905 citations

    11

    h-index

  2. Nucleic Acids Research

    11 publications · 567 citations

    11

    h-index

  3. Molecular and Cellular Biology

    MCB · 7 publications · 669 citations

    7

    h-index

  4. RNA

    6 publications · 172 citations

    6

    h-index

  5. Genes & Development

    6 publications · 636 citations

    6

    h-index

1–5