Cleaning Validation

Cleaning Validation is a systematic and documented process within pharmaceutical manufacturing that belongs to the broader category of process validation, specifically designed to provide scientific evidence that cleaning procedures consistently remove residues to predetermined acceptance criteria to prevent cross-contamination.

Publications

2.1K

Citations

280

Authors

100

Institutions

Publications per year

2017–2026

Parents

Pharmaceutical InspectionPharmaceutical ManufacturingProcess Validation

Children

Acceptance Criteria EstablishmentClean-in-place ValidationCleaning Cycle DevelopmentCleaning Procedure ValidationCleaning Process QualificationDedicated Equipment CleaningEquipment Surface Residue LimitsManual Cleaning ValidationMaximum Allowable CarryoverMicrobial Residue Control

Publications

A modified ATP benchmark for evaluating the cleaning of some hospital environmental surfaces

Thomas P. Lewis, Chris Griffith, Melanie Gallo et al. · Journal of Hospital Infection · 2008 · 199 citations

Architecture, Environmental Engineering, Water Treatment +11

Challenges in Cleaning: Recent Developments and Future Prospects

D.I. Wilson · Heat Transfer Engineering · 2005 · 130 citations

Engineering, Chemical Engineering, Materials Engineering +17

DETERMINING CLEANING VALIDATION ACCEPTANCE LIMITS FOR PHARMACEUTICAL MANUFACTURING OPERATIONS

G. L. Fourman, M. V. Mullen · Pharmaceutical technology · 1993 · 88 citations

Pharmacy, Quality Management, Pharmaceutical Manufacturing +5

An evaluation of patient area cleaning in 3 hospitals using a novel targeting methodology

Philip Carling, Janet Briggs, Deborah Hylander et al. · American Journal of Infection Control · 2006 · 79 citations

Health Professions, Health Services Administration, Hospital Administration +11

Effectiveness and harmfulness evaluation of graffiti cleaning by mechanical, chemical and laser procedures on granite

J.S. Pozo-António, T. Rivas, M.P. Fiorucci et al. · Microchemical Journal · 2015 · 69 citations

Architecture, Environmental Engineering, Surface Engineering +10

1–5 of 73

Authors

280

JT
Joseph T. Rubino
University of North Carolina at Chapel Hill, United States
2 publications · 33 citations
2
h-index
TM
Tahseen Mirza
United States Food and Drug Administration, United States
2 publications · 63 citations
2
h-index
RW
Robert W. Woodeshick
Wilmington University, United States
2 publications · 33 citations
2
h-index
RC
Ron C George
The Ohio State University at Marion, United States
2 publications · 63 citations
2
h-index
RJ
Richard J. Forsyth
United States Military Academy, United States
2 publications · 28 citations
2
h-index

1–5 of 280

Institutions

100

1–8 of 100

Venues

Journal of Pharmaceutical and Biomedical Analysis
10 publications · 269 citations
10
h-index
Pharmaceutical technology
6 publications · 200 citations
6
h-index
PubMed
Repository · 5 publications · 83 citations
5
h-index
Journal of Hospital Infection
3 publications · 234 citations
3
h-index
American Journal of Infection Control
AJIC · 3 publications · 124 citations
3
h-index

1–5