Concepedia

Clarithromycin Resistance

Clarithromycin Resistance is a microbial resistance phenotype characterized by the reduced susceptibility of Helicobacter pylori to clarithromycin, typically due to point mutations in the 23S rRNA gene, which impedes the antibiotic's binding to the bacterial ribosome and thereby compromises the efficacy of eradication therapy.

1.1K

Publications

55K

Citations

5.5K

Authors

1.6K

Institutions

Publications per year

2017–2026

303

Parents

Publications

1.1K

<i>Helicobacter pylori</i> resistance to antibiotics in Europe and its relationship to antibiotic consumption

Françis Mégraud, Samuel Coenen, Ann Versporten et al. · Gut · 2012 · 832 citations

, , +14

A Novel Gene, <i>erm</i> (41), Confers Inducible Macrolide Resistance to Clinical Isolates of <i>Mycobacterium abscessus</i> but Is Absent from <i>Mycobacterium chelonae</i>

Kevin A. Nash, Barbara A. Brown‐Elliott, Richard J. Wallace · Antimicrobial Agents and Chemotherapy · 2009 · 644 citations · Full text

, , +16

Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study

Surbhi Malhotra‐Kumar, Christine Lammens, Samuel Coenen et al. · The Lancet · 2007 · 553 citations

, , +17

<i>Mycobacterium abscessus</i>Complex Infections in Humans

Meng‐Rui Lee, Wang‐Huei Sheng, Chien‐Ching Hung et al. · Emerging infectious diseases · 2015 · 510 citations · Full text

, , +17

Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori

James Versalovic, Dee Shortridge, K. Kibler et al. · Antimicrobial Agents and Chemotherapy · 1996 · 504 citations · Full text

, , +17

1–5 of 1.1K

Authors

5.5K

  1. FM
    Françis Mégraud

    Université de Bordeaux, France

    35 publications · 3.9K citations

    25

    h-index

  2. DY
    David Y. Graham

    Baylor College of Medicine, United States

    21 publications · 1.8K citations

    18

    h-index

  3. RJ
    Richard J. Wallace

    The University of Texas Health Science Center at Tyler, United States

    20 publications · 3.4K citations

    18

    h-index

  4. AZ
    Angelo Zullo

    Ospedale Regina Margherita, Italy

    17 publications · 907 citations

    17

    h-index

  5. YY
    Yoshio Yamaoka

    Kyoto University, Japan

    14 publications · 685 citations

    14

    h-index

1–5 of 5.5K

Institutions

1.6K

  1. Baylor College of Medicine

    Houston, United States

    25 h-index

    95 publications

    13.4K citations

  2. Inserm

    Paris, France

    21 h-index

    55 publications

    4.7K citations

  3. The University of Texas Health Science Center at Tyler

    Tyler, United States

    18 h-index

    88 publications

    16.1K citations

  4. University of Bologna

    Bologna, Italy

    18 h-index

    84 publications

    3.6K citations

  5. Oita University

    Ōita, Japan

    18 h-index

    82 publications

    4.1K citations

  6. Hôpital Pellegrin

    Bordeaux, France

    15 h-index

    48 publications

    5.2K citations

  7. Ospedale Regina Margherita

    Turin, Italy

    15 h-index

    28 publications

    1.8K citations

  8. Université de Bordeaux

    Bordeaux, France

    15 h-index

    37 publications

    4.4K citations

1–8 of 1.6K

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 103 publications · 8.7K citations

    52

    h-index

  2. Helicobacter

    94 publications · 4.7K citations

    42

    h-index

  3. Journal of Clinical Microbiology

    JCM · 56 publications · 4K citations

    40

    h-index

  4. Journal of Antimicrobial Chemotherapy

    JAC · 57 publications · 3.7K citations

    35

    h-index

  5. Alimentary Pharmacology & Therapeutics

    45 publications · 2.3K citations

    30

    h-index

1–5