Concepedia

Clamp Opening

Clamp Opening is a biochemical mechanism within the DNA replication machinery that facilitates the transient disassembly of the sliding clamp ring, allowing its loading onto primed DNA by the clamp loader complex.

96

Publications

6.5K

Citations

347

Authors

125

Institutions

Publications per year

2017–2026

19

Parents

Publications

96

The ATPase cycle of Hsp90 drives a molecular ‘clamp’ via transient dimerization of the N‐terminal domains

Chrisostomos Prodromou · The EMBO Journal · 2000 · 490 citations · Full text

, , +15

Sequence-Specific DNA Binding by a Short Peptide Dimer

Robert V. Talanian, C. James McKnight, Peter S. Kim · Science · 1990 · 316 citations

, , +13

A Phenylalanine Clamp Catalyzes Protein Translocation Through the Anthrax Toxin Pore

Bryan A. Krantz, Roman A. Melnyk, Sen Zhang et al. · Science · 2005 · 300 citations · Full text

, , +15

Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III

David Jeruzalmi, Olga Yurieva, Yanxiang Zhao et al. · Cell · 2001 · 264 citations · Full text

, , +17

Architecture of initiation-competent 12-subunit RNA polymerase II

Karim‐Jean Armache, Hubert Kettenberger, Patrick Cramer · Proceedings of the National Academy of Sciences · 2003 · 256 citations · Full text

, , +17

1–5 of 96

Authors

347

  1. MO
    Mike O’Donnell

    Howard Hughes Medical Institute, United States

    11 publications · 1K citations

    11

    h-index

  2. MH
    Manju Hingorani

    Wesleyan University, United States

    6 publications · 558 citations

    6

    h-index

  3. SJ
    Stephen J. Benkovic

    Pennsylvania State University, United States

    5 publications · 156 citations

    5

    h-index

  4. BA
    Brian A. Kelch

    University of Massachusetts Chan Medical School, United States

    3 publications · 353 citations

    4

    h-index

  5. II
    Ivaylo Ivanov

    Georgia State University, United States

    4 publications · 78 citations

    4

    h-index

1–5 of 347

Institutions

125

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    34 publications

    4.8K citations

  2. Rockefeller University

    New York, United States

    12 h-index

    35 publications

    4.2K citations

  3. Pennsylvania State University

    State College, United States

    7 h-index

    22 publications

    1.1K citations

  4. Georgia State University

    Atlanta, United States

    4 h-index

    18 publications

    309 citations

  5. University of Florida

    Gainesville, United States

    4 h-index

    17 publications

    583 citations

  6. University of Wollongong

    Wollongong, Australia

    3 h-index

    3 publications

    97 citations

  7. Scripps Research Institute

    San Diego, United States

    3 h-index

    8 publications

    564 citations

  8. St. Jude Children's Research Hospital

    Memphis, United States

    3 h-index

    14 publications

    707 citations

1–8 of 125

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 626 citations

    12

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 647 citations

    6

    h-index

  3. Biochemistry

    6 publications · 224 citations

    6

    h-index

  4. Nucleic Acids Research

    6 publications · 203 citations

    6

    h-index

  5. Injury

    5 publications · 238 citations

    5

    h-index

1–5