Concepedia

Clamp Loader-dna Interaction

Clamp Loader-DNA Interaction is a molecular mechanism in DNA replication that refers to the specific recognition and transient binding of the clamp loader complex to DNA, enabling the ATP-dependent loading of the sliding clamp onto primed DNA sites to facilitate polymerase processivity.

67

Publications

4.7K

Citations

242

Authors

91

Institutions

Publications per year

2017–2026

11

Parents

Publications

67

Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA

Viola Ellison, Bruce Stillman · PLoS Biology · 2003 · 364 citations · Full text

, , +17

Crystal Structure of the Processivity Clamp Loader Gamma (γ) Complex of E. coli DNA Polymerase III

David Jeruzalmi, Mike O’Donnell, John Kuriyan · Cell · 2001 · 318 citations · Full text

, , +16

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex <i>in vitro</i>

Vladimir P. Bermudez, Laura A. Lindsey‐Boltz, Anthony J. Cesare et al. · Proceedings of the National Academy of Sciences · 2003 · 316 citations · Full text

, , +17

The capture of a DNA double helix by an ATP-dependent protein clamp: A key step in DNA transport by type II DNA topoisomerases

Joaquím Roca, James C. Wang · Cell · 1992 · 312 citations

, , +7

Yeast Rad17/Mec3/Ddc1: A sliding clamp for the DNA damage checkpoint

Jerzy Majka, Peter Burgers · Proceedings of the National Academy of Sciences · 2003 · 261 citations · Full text

, , +17

1–5 of 67

Authors

242

  1. MO
    Mike O’Donnell

    Howard Hughes Medical Institute, United States

    18 publications · 1.4K citations

    17

    h-index

  2. LB
    Linda B. Bloom

    University of Florida, United States

    11 publications · 346 citations

    11

    h-index

  3. MH
    Manju Hingorani

    Wesleyan University, United States

    6 publications · 319 citations

    6

    h-index

  4. JK
    John Kuriyan

    Howard Hughes Medical Institute, United States

    5 publications · 726 citations

    5

    h-index

  5. NY
    Nina Y. Yao

    Howard Hughes Medical Institute, United States

    5 publications · 242 citations

    5

    h-index

1–5 of 242

Institutions

91

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    17 h-index

    43 publications

    3.6K citations

  2. Rockefeller University

    New York, United States

    16 h-index

    35 publications

    2.6K citations

  3. University of Florida

    Gainesville, United States

    10 h-index

    39 publications

    1.2K citations

  4. University of California, Berkeley

    Berkeley, United States

    6 h-index

    14 publications

    1.5K citations

  5. Pennsylvania State University

    State College, United States

    5 h-index

    19 publications

    757 citations

  6. Kyushu University

    Fukuoka, Japan

    5 h-index

    16 publications

    576 citations

  7. Wesleyan University

    Middletown, United States

    5 h-index

    13 publications

    665 citations

  8. Washington University in St. Louis

    St Louis, United States

    4 h-index

    7 publications

    950 citations

1–8 of 91

Venues

  1. Journal of Biological Chemistry

    JBC · 16 publications · 667 citations

    15

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 775 citations

    6

    h-index

  3. Nucleic Acids Research

    5 publications · 95 citations

    5

    h-index

  4. Journal of Molecular Biology

    JMB · 5 publications · 240 citations

    5

    h-index

  5. eLife

    4 publications · 166 citations

    4

    h-index

1–5