Concepedia

Chromatin Position Effects

Chromatin Position Effects is a phenomenon in molecular genetics whereby the local chromatin environment at a specific genomic integration site influences the expression level and stability of a transgene, leading to variable transcriptional activity independent of the transgene's intrinsic regulatory elements.

91

Publications

6.3K

Citations

331

Authors

128

Institutions

Publications per year

2017–2026

7

Variants

Position EffectPosition Effects

Parents

Publications

91

Position effect variegation in Drosophila is associated with an altered chromatin structure.

Lori L. Wallrath, Sarah C. R. Elgin · Genes & Development · 1995 · 476 citations · Full text

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Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P element insertional mutagenesis.

Gary H. Karpen, Allan C. Spradling · Genetics · 1992 · 404 citations · Full text

, , +16

Locus Control Region Function and Heterochromatin-Induced Position Effect Variegation

Richard Festenstein, Mauro Tolaini, Paola Corbella et al. · Science · 1996 · 367 citations

, , +16

Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

Waseem Akhtar, Johann de Jong, Alexey V. Pindyurin et al. · Cell · 2013 · 343 citations

, , +15

A drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation

Tatlana I. Gerasimova, David A. Gdula, Denis V. Gerasimov et al. · Cell · 1995 · 299 citations · Full text

, , +17

1–5 of 91

Authors

331

  1. SC
    Sarah C. R. Elgin

    Washington University in St. Louis, United States

    5 publications · 641 citations

    5

    h-index

  2. SH
    Steven Henikoff

    Fred Hutch Cancer Center, United States

    4 publications · 309 citations

    4

    h-index

  3. KM
    Kristen M. Johansen

    Iowa State University, United States

    3 publications · 77 citations

    3

    h-index

  4. BT
    Barbara T. Wakimoto

    University of Washington, United States

    3 publications · 384 citations

    3

    h-index

  5. GH
    Gary H. Karpen

    Lawrence Berkeley National Laboratory, United States

    3 publications · 446 citations

    3

    h-index

1–5 of 331

Institutions

128

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    10 publications

    1.2K citations

  2. Washington University in St. Louis

    St Louis, United States

    5 h-index

    14 publications

    1.4K citations

  3. University of Geneva

    Geneva, Switzerland

    5 h-index

    15 publications

    1K citations

  4. Fred Hutch Cancer Center

    Seattle, United States

    4 h-index

    10 publications

    499 citations

  5. University of Connecticut

    Storrs, United States

    3 h-index

    6 publications

    240 citations

  6. University of British Columbia

    Vancouver, Canada

    3 h-index

    6 publications

    242 citations

  7. Iowa State University

    Ames, United States

    3 h-index

    16 publications

    413 citations

  8. Heidelberg University

    Heidelberg, Germany

    3 h-index

    5 publications

    355 citations

1–8 of 128

Venues

  1. Genetics

    29 publications · 1.6K citations

    19

    h-index

  2. Chromosoma

    6 publications · 461 citations

    6

    h-index

  3. Development

    3 publications · 102 citations

    3

    h-index

  4. 3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 170 citations

    3

    h-index

1–5