Concepedia

Chromatin Loop Extrusion

Chromatin Loop Extrusion is a molecular mechanism in three-dimensional genome organization whereby cohesin complexes progressively recruit and translocate chromatin fibers to form increasingly larger loops, thereby establishing topologically associating domains through constrained diffusion and directional extrusion.

141

Publications

18.4K

Citations

655

Authors

259

Institutions

Publications per year

2017–2026

133

Parents

Publications

141

Formation of Chromosomal Domains by Loop Extrusion

Geoffrey Fudenberg, Maxim Imakaev, Carolyn Lu et al. · Cell Reports · 2016 · 2.2K citations · Full text

, , +17

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

Adrian L. Sanborn, Suhas S.P. Rao, Su-Chen Huang et al. · Proceedings of the National Academy of Sciences · 2015 · 1.9K citations · Full text

, , +17

DNA loop extrusion by human cohesin

Iain F. Davidson, Benedikt Bauer, Daniela Goetz et al. · Science · 2019 · 955 citations

, , +17

Real-time imaging of DNA loop extrusion by condensin

Mahipal Ganji, Indra A. Shaltiël, S. Bisht et al. · Science · 2018 · 888 citations · Full text

, , +17

Human cohesin compacts DNA by loop extrusion

Yoori Kim, Zhubing Shi, Hongshan Zhang et al. · Science · 2019 · 780 citations · Full text

, , +17

1–5 of 141

Authors

655

  1. LA
    Leonid A. Mirny

    Massachusetts Institute of Technology, United States

    23 publications · 5.5K citations

    20

    h-index

  2. JP
    Jan‐Michael Peters

    Research Institute of Molecular Pathology, Austria

    20 publications · 2.8K citations

    15

    h-index

  3. IF
    Iain F. Davidson

    Research Institute of Molecular Pathology, Austria

    15 publications · 2.1K citations

    12

    h-index

  4. MI
    Maxim Imakaev

    Massachusetts Institute of Technology, United States

    12 publications · 4.2K citations

    12

    h-index

  5. HB
    Hugo B. Brandão

    Massachusetts Institute of Technology, United States

    11 publications · 1.7K citations

    11

    h-index

1–5 of 655

Institutions

259

  1. Massachusetts Institute of Technology

    Cambridge, United States

    23 h-index

    85 publications

    23.8K citations

  2. Research Institute of Molecular Pathology

    Vienna, Austria

    16 h-index

    114 publications

    15.3K citations

  3. University of Edinburgh

    Edinburgh, United Kingdom

    15 h-index

    65 publications

    4.3K citations

  4. Harvard University

    Cambridge, United States

    15 h-index

    62 publications

    20.5K citations

  5. Vienna Biocenter

    Vienna, Austria

    12 h-index

    78 publications

    4.8K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    54 publications

    6K citations

  7. Delft University of Technology

    Delft, The Netherlands

    11 h-index

    58 publications

    7.2K citations

  8. Institute of Molecular Biotechnology

    Vienna, Austria

    11 h-index

    28 publications

    2.4K citations

1–8 of 259

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 40 publications · 868 citations

    20

    h-index

  2. eLife

    12 publications · 1.4K citations

    12

    h-index

  3. Nature Communications

    12 publications · 693 citations

    11

    h-index

  4. Nature

    9 publications · 1.7K citations

    9

    h-index

  5. Science

    8 publications · 3.7K citations

    8

    h-index

1–5