Concepedia

Chemical Reprogramming

Chemical Reprogramming is a method in stem cell biology that induces pluripotency in somatic cells through the application of small molecules, distinguishing it from genetic or viral reprogramming approaches by its reliance solely on chemical compounds to modulate cellular signaling pathways and epigenetic states.

34

Publications

3.8K

Citations

293

Authors

92

Institutions

Publications per year

2017–2026

25

Variants

Small-molecule Reprogramming

Parents

Publications

34

Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds

Pingping Hou, Yanqin Li, Xu Zhang et al. · Science · 2013 · 1.4K citations

, , +17

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

Athanasia D. Panopoulos, Óscar Yanes, Sergio Ruiz et al. · Cell Research · 2011 · 498 citations · Full text

, , +14

Chemical reprogramming of human somatic cells to pluripotent stem cells

Jingyang Guan, Guan Wang, Jinlin Wang et al. · Nature · 2022 · 373 citations

, , +14

A XEN-like State Bridges Somatic Cells to Pluripotency during Chemical Reprogramming

Yang Zhao, Ting Zhao, Jingyang Guan et al. · Cell · 2015 · 267 citations · Full text

, , +11

Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming

Ting Zhao, Yao Fu, Jialiang Zhu et al. · Cell stem cell · 2018 · 175 citations · Full text

, , +12

1–5 of 34

Authors

293

  1. HD
    Hongkui Deng

    Peking University, China

    8 publications · 2.6K citations

    8

    h-index

  2. JG
    Jingyang Guan

    Peking University, China

    6 publications · 2.3K citations

    6

    h-index

  3. CL
    Cheng Li

    Peking University, China

    5 publications · 818 citations

    5

    h-index

  4. YZ
    Yang Zhao

    Peking University, China

    4 publications · 1.7K citations

    4

    h-index

  5. YF
    Yao Fu

    Center for Life Sciences, China

    4 publications · 942 citations

    4

    h-index

1–5 of 293

Institutions

92

  1. Peking University

    Beijing, China

    10 h-index

    135 publications

    30.1K citations

  2. Center for Life Sciences

    Beijing, China

    10 h-index

    112 publications

    37.7K citations

  3. State Key Laboratory of Natural and Biomimetic Drugs

    Beijing, China

    4 h-index

    27 publications

    2.5K citations

  4. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    26 publications

    969 citations

  5. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    12 publications

    520 citations

  6. Tsinghua University

    Beijing, China

    3 h-index

    4 publications

    462 citations

  7. Harvard University

    Cambridge, United States

    2 h-index

    19 publications

    520 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    3 publications

    578 citations

1–8 of 92

Venues

  1. Cell stem cell

    4 publications · 424 citations

    4

    h-index

  2. Nature Chemical Biology

    3 publications · 144 citations

    3

    h-index

  3. Nature

    2 publications · 387 citations

    2

    h-index

  4. eLife

    2 publications · 56 citations

    2

    h-index

  5. Angewandte Chemie International Edition

    1 publications · 12 citations

    1

    h-index

1–5