Bioconductor: open software development for computational biology and bioinformatics

Robert Gentleman, Vincent J. Carey, Douglas M. Bates, +22

Genome biology

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

Arindam Bhattacharjee, William G. Richards, Jane Staunton, +16

Proceedings of the National Academy of Sciences

EngineeringPathologyCancer DeathCancer BiologyGene Expression Profiling +15

Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

Xuemei Xie, Qiang Shi, Peng Wu, +14

Nature Immunology

InflammationFunctional GenomicsAutoimmune DiseaseSingle Cell SequencingMedicine +9

Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency

Yang Yang, Bei Liu, Jun Xu, +31

Cell

Regenerative MedicineEmbryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyPluripotent Stem Cells +13

CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia

Lei Xu, Jun Wang, Yulin Liu, +20

New England Journal of Medicine

Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice

Yusheng Cai, Huanhuan Zhou, Yinhua Zhu, +11

Cell Research

Chemical reprogramming of human somatic cells to pluripotent stem cells

Jingyang Guan, Guan Wang, Jinlin Wang, +23

Nature

Tissue EngineeringInduced Pluripotent Stem CellEngineeringInduced Pluripotent Stem CellsCell Reprogramming +9

Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis

Faith E. Davies, Ann Dring, Cheng Li, +20

Blood

Long-term functional maintenance of primary human hepatocytes in vitro

Chengang Xiang, Yuanyuan Du, Gaofan Meng, +24

Science

SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis

Lan Fang, Hongqi Teng, Yilin Wang, +25

Cancer Cell

Set1a-mediated Mono-methylationNuclear ExportCell RegulationMedicineEpigenetic Change +10