Concepedia

Checkpoint Protein Interactions

Checkpoint Protein Interactions is a molecular mechanism in DNA replication and repair processes whereby sliding clamp proteins selectively recruit and regulate checkpoint signaling proteins to coordinate cell cycle progression and genomic stability maintenance in response to replication stress or DNA damage.

179

Publications

18.4K

Citations

729

Authors

252

Institutions

Publications per year

2017–2026

12

Parents

Publications

179

Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

Jacqueline M. Gulbis, Zvi Kelman, J Hurwitz et al. · Cell · 1996 · 810 citations · Full text

, , +13

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

Guowei Fang, Hongtao Yu, Marc W. Kirschner · Genes & Development · 1998 · 592 citations · Full text

, , +17

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

Jeremy Minshull, Hong Sun, Nicholas K. Tonks et al. · Cell · 1994 · 411 citations

, , +14

Checkpoint Protein BubR1 Acts Synergistically with Mad2 to Inhibit Anaphase-promoting Complex

Guowei Fang · Molecular Biology of the Cell · 2002 · 328 citations · Full text

, , +17

Spindle Checkpoint Protein Xmad1 Recruits Xmad2 to Unattached Kinetochores

Rey‐Huei Chen, Andrej Shevchenko, Matthias Mann et al. · The Journal of Cell Biology · 1998 · 308 citations · Full text

, , +17

1–5 of 179

Authors

729

  1. PR
    Paul Russell

    Scripps Research Institute, United States

    7 publications · 697 citations

    7

    h-index

  2. WG
    William G. Dunphy

    California Institute of Technology, United States

    6 publications · 575 citations

    6

    h-index

  3. HM
    Hisao Masai

    Tokyo Metropolitan Institute of Medical Science, Japan

    6 publications · 366 citations

    6

    h-index

  4. AS
    Aziz Sancar

    University of North Carolina at Chapel Hill, United States

    5 publications · 284 citations

    5

    h-index

  5. AL
    A-Lien Lu

    University of Maryland, Baltimore, United States

    5 publications · 345 citations

    5

    h-index

1–5 of 729

Institutions

252

  1. Scripps Research Institute

    San Diego, United States

    10 h-index

    28 publications

    2.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    8 h-index

    15 publications

    2.9K citations

  3. Cancer Research UK

    London, United Kingdom

    8 h-index

    21 publications

    1.6K citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    7 h-index

    19 publications

    1.1K citations

  5. Harvard University

    Cambridge, United States

    7 h-index

    30 publications

    4.3K citations

  6. University of Maryland, Baltimore

    Baltimore, United States

    6 h-index

    28 publications

    1.7K citations

  7. Tokyo Metropolitan Institute of Medical Science

    Tokyo, Japan

    6 h-index

    18 publications

    968 citations

  8. California Institute of Technology

    Pasadena, United States

    6 h-index

    14 publications

    1.4K citations

1–8 of 252

Venues

  1. Journal of Biological Chemistry

    JBC · 37 publications · 2.9K citations

    29

    h-index

  2. Molecular and Cellular Biology

    MCB · 14 publications · 1.8K citations

    14

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.4K citations

    12

    h-index

  4. Nucleic Acids Research

    9 publications · 333 citations

    9

    h-index

  5. Genes & Development

    8 publications · 1.9K citations

    8

    h-index

1–5