Concepedia

Cellular Resource Competition

Cellular Resource Competition is a theoretical construct in synthetic biology circuit modeling that refers to the phenomenon wherein heterologous genetic circuits compete for limited intracellular resources, such as ribosomes, RNA polymerases, nucleotides, and amino acids, thereby affecting circuit performance and predictability.

27

Publications

1.4K

Citations

92

Authors

41

Institutions

Publications per year

2017–2026

11

Parents

Publications

27

Principles of cellular resource allocation revealed by condition-dependent proteome profiling

Eyal Metzl-Raz, Moshe Kafri, Gilad Yaakov et al. · eLife · 2017 · 265 citations · Full text

, , +17

Dynamic allocation of orthogonal ribosomes facilitates uncoupling of co-expressed genes

Alexander P. S. Darlington, Juhyun Kim, José I. Jiménez et al. · Nature Communications · 2018 · 162 citations · Full text

, , +17

Coinfecting Prion Strains Compete for a Limiting Cellular Resource

Ronald A. Shikiya, Jacob I. Ayers, Charles R. Schutt et al. · Journal of Virology · 2010 · 85 citations

, , +16

Resource competition as a mechanism for B cell homeostasis

Angela R. McLean, M. Manuela Rosado, Fabien Agenès et al. · Proceedings of the National Academy of Sciences · 1997 · 79 citations

, , +13

Winner-takes-all resource competition redirects cascading cell fate transitions

Rong Zhang, Hanah Goetz, Juan Melendez-Alvarez et al. · Nature Communications · 2021 · 78 citations · Full text

, , +16

1–5 of 27

Authors

92

  1. AA
    António A. Freitas

    Institut Pasteur, France

    3 publications · 183 citations

    3

    h-index

  2. EM
    Eyal Metzl-Raz

    Weizmann Institute of Science, Israel

    2 publications · 275 citations

    2

    h-index

  3. IS
    Ilya Soifer

    Weizmann Institute of Science, Israel

    2 publications · 275 citations

    2

    h-index

  4. MK
    Moshe Kafri

    Weizmann Institute of Science, Israel

    2 publications · 275 citations

    2

    h-index

  5. XT
    Xiao‐Jun Tian

    Arizona State University, United States

    2 publications · 90 citations

    2

    h-index

1–5 of 92

Institutions

41

  1. University of Oxford

    Oxford, United Kingdom

    4 h-index

    10 publications

    572 citations

  2. Institut Pasteur

    Paris, France

    3 h-index

    10 publications

    715 citations

  3. University College London

    London, United Kingdom

    2 h-index

    3 publications

    127 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    5 publications

    320 citations

  5. Politecnico di Torino

    Turin, Italy

    2 h-index

    4 publications

    81 citations

  6. Arizona State University

    Tempe, United States

    2 h-index

    9 publications

    504 citations

  7. University of California, Berkeley

    Berkeley, United States

    2 h-index

    6 publications

    320 citations

  8. Utrecht University

    Utrecht, The Netherlands

    2 h-index

    5 publications

    260 citations

1–8 of 41

Venues

  1. Nature Communications

    3 publications · 303 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 136 citations

    2

    h-index

  3. European Journal of Immunology

    EJI · 1 publications · 72 citations

    1

    h-index

  4. npj Systems Biology and Applications

    1 publications · 26 citations

    1

    h-index

  5. Physical Review Letters

    PRL · 1 publications · 51 citations

    1

    h-index

1–5