Concepedia

Cell-type Composition Adjustment

Cell-Type Composition Adjustment is a statistical method in epigenetic epidemiology that accounts for variation in tissue-specific cellular proportions to isolate true epigenetic signals from confounding effects due to heterogeneous cell-type distributions in bulk tissue samples.

54

Publications

5.4K

Citations

359

Authors

175

Institutions

Publications per year

2017–2026

33

Variants

Cell-type Correction

Parents

Publications

54

Accounting for cellular heterogeneity is critical in epigenome-wide association studies

Andrew E. Jaffe, Rafael A. Irizarry · Genome biology · 2014 · 1.2K citations · Full text

, , +14

Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi

Jean-Philippe Fortin, Timothy J. Triche, Kasper D. Hansen · Bioinformatics · 2016 · 931 citations · Full text

, , +14

Reference-free cell mixture adjustments in analysis of DNA methylation data

E. Andrés Houseman, John Molitor, Carmen J. Marsit · Bioinformatics · 2014 · 474 citations · Full text

, , +10

Epigenome-wide association studies without the need for cell-type composition

James Zou, Christoph Lippert, David Heckerman et al. · Nature Methods · 2014 · 236 citations

, , +14

Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data

Kristina Gervin, Lucas A. Salas, Kelly M. Bakulski et al. · Clinical Epigenetics · 2019 · 234 citations · Full text

, , +15

1–5 of 54

Authors

359

  1. KM
    Kelly M. Bakulski

    University of Michigan, United States

    4 publications · 329 citations

    4

    h-index

  2. RL
    Robert Lyle

    Oslo University Hospital, Norway

    4 publications · 388 citations

    4

    h-index

  3. RA
    Rafael A. Irizarry

    Johns Hopkins University, United States

    3 publications · 1.3K citations

    3

    h-index

  4. JF
    Janine F. Felix

    Erasmus MC, Netherlands

    3 publications · 370 citations

    3

    h-index

  5. MJ
    Meaghan J. Jones

    University of British Columbia, Canada

    3 publications · 326 citations

    3

    h-index

1–5 of 359

Institutions

175

  1. Johns Hopkins University

    Baltimore, United States

    8 h-index

    19 publications

    3.8K citations

  2. University of California, San Francisco

    San Francisco, United States

    5 h-index

    7 publications

    479 citations

  3. University of Michigan

    Ann Arbor, United States

    5 h-index

    11 publications

    780 citations

  4. University of British Columbia

    Vancouver, Canada

    4 h-index

    14 publications

    727 citations

  5. Dana-Farber Cancer Institute

    Boston, United States

    4 h-index

    4 publications

    1.4K citations

  6. Oslo University Hospital

    Oslo, Norway

    4 h-index

    8 publications

    832 citations

  7. Harvard University

    Cambridge, United States

    4 h-index

    5 publications

    1.4K citations

  8. University of Oslo

    Oslo, Norway

    4 h-index

    10 publications

    905 citations

1–8 of 175

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 5 publications · 99 citations

    5

    h-index

  2. Clinical Epigenetics

    4 publications · 409 citations

    4

    h-index

  3. Epigenetics

    3 publications · 181 citations

    3

    h-index

  4. Bioinformatics

    3 publications · 1.6K citations

    3

    h-index

  5. Genome biology

    3 publications · 1.3K citations

    3

    h-index

1–5