Concepedia

Cell-selex

Cell-SELEX is a systematic evolution method of ligands by exponential enrichment that uses whole living cells as targets to select nucleic acid aptamers capable of specifically binding to cell surface biomarkers, thereby enabling the identification of molecular recognition elements for complex cellular phenotypes.

224

Publications

17.6K

Citations

1.1K

Authors

366

Institutions

Publications per year

2017–2026

91

Variants

Cell-based Selex

Parents

Publications

224

Development of DNA aptamers using Cell-SELEX

Kwame Sefah, Dihua Shangguan, Xiangling Xiong et al. · Nature Protocols · 2010 · 909 citations

, , +5

Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach

Xiaohong Fang, Weihong Tan · Accounts of Chemical Research · 2009 · 743 citations

, , +16

A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment

Dion A. Daniels, Hang Chen, Brian J. Hicke et al. · Proceedings of the National Academy of Sciences · 2003 · 569 citations · Full text

, , +16

Selection of Aptamers for Molecular Recognition and Characterization of Cancer Cells

Zhiwen Tang, Dihua Shangguan, Kemin Wang et al. · Analytical Chemistry · 2007 · 481 citations

, , +11

Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

Dihua Shangguan, Zehui Cao, Ling Meng et al. · Journal of Proteome Research · 2008 · 462 citations · Full text

, , +16

1–5 of 224

Authors

1.1K

  1. WT
    Weihong Tan

    Hunan University, China

    43 publications · 7.3K citations

    35

    h-index

  2. DS
    Dihua Shangguan

    Chinese Academy of Sciences, China

    16 publications · 4.3K citations

    16

    h-index

  3. KS
    Kwame Sefah

    University of Florida, United States

    13 publications · 3.1K citations

    13

    h-index

  4. ZT
    Zhiwen Tang

    University of Florida, United States

    7 publications · 1.5K citations

    7

    h-index

  5. KW
    Kemin Wang

    Hunan University, China

    7 publications · 758 citations

    7

    h-index

1–5 of 1.1K

Institutions

366

  1. University of Florida

    Gainesville, United States

    28 h-index

    145 publications

    34.6K citations

  2. Hunan University

    Changsha, China

    23 h-index

    159 publications

    16.7K citations

  3. Interface (United States)

    La Grange, United States

    20 h-index

    86 publications

    19.6K citations

  4. University of Florida Health

    Gainesville, United States

    18 h-index

    69 publications

    12.2K citations

  5. Chinese Academy of Sciences

    Beijing, China

    15 h-index

    73 publications

    8.6K citations

  6. State Key Laboratory of Chemobiosensing and Chemometrics

    Changsha, China

    13 h-index

    73 publications

    6.9K citations

  7. Beijing National Laboratory for Molecular Sciences

    Beijing, China

    11 h-index

    61 publications

    7K citations

  8. Central South University

    Changsha, China

    9 h-index

    52 publications

    3.2K citations

1–8 of 366

Venues

  1. PLoS ONE

    22 publications · 1.3K citations

    20

    h-index

  2. Analytical Chemistry

    15 publications · 2.2K citations

    15

    h-index

  3. Molecular Therapy — Nucleic Acids

    11 publications · 604 citations

    11

    h-index

  4. Scientific Reports

    10 publications · 480 citations

    10

    h-index

  5. Methods in molecular biology

    Book series · 6 publications · 208 citations

    6

    h-index

1–5