Concepedia

Cell-free Prototyping

Cell-Free Prototyping is a research methodology in synthetic biology that enables the rapid design, testing, and optimization of biological systems using cell-free expression platforms, distinguished from in vivo approaches by its reliance on acellular environments to decouple genetic circuit function from cellular constraints.

62

Publications

4.7K

Citations

275

Authors

92

Institutions

Publications per year

2017–2026

34

Parents

Publications

62

Linear DNA for Rapid Prototyping of Synthetic Biological Circuits in an <i>Escherichia coli</i> Based TX-TL Cell-Free System

Zachary Z. Sun, Enoch Yeung, Clarmyra A. Hayes et al. · ACS Synthetic Biology · 2013 · 327 citations

, , +17

A cell-free framework for rapid biosynthetic pathway prototyping and enzyme discovery

Ashty S. Karim, Michael C. Jewett · Metabolic Engineering · 2016 · 261 citations

, , +16

A receptor molecule for estrogens: studies using a cell-free system.

D O Toft, G. Shyamala, J Górski · Proceedings of the National Academy of Sciences · 1967 · 224 citations

, , +14

Gene Circuit Performance Characterization and Resource Usage in a Cell-Free “Breadboard”

Dan Siegal‐Gaskins, Zoltán A. Tuza, Jongmin Kim et al. · ACS Synthetic Biology · 2014 · 211 citations

, , +17

Simple procedures for the construction of a robust and cost-effective cell-free protein synthesis system

Tae‐Wan Kim, Jung‐Won Keum, In‐Seok Oh et al. · Journal of Biotechnology · 2006 · 197 citations

, , +13

1–5 of 62

Authors

275

  1. MC
    Michael C. Jewett

    Northwestern University, United States

    12 publications · 989 citations

    11

    h-index

  2. VN
    Vincent Noireaux

    University of Minnesota, United States

    6 publications · 847 citations

    6

    h-index

  3. AS
    Ashty S. Karim

    Northwestern University, United States

    5 publications · 574 citations

    5

    h-index

  4. PS
    Paul S. Freemont

    Imperial College London, United Kingdom

    4 publications · 463 citations

    4

    h-index

  5. RM
    Richard M. Murray

    California Institute of Technology, United States

    4 publications · 694 citations

    4

    h-index

1–5 of 275

Institutions

92

  1. Northwestern University

    Evanston, United States

    10 h-index

    41 publications

    3.6K citations

  2. University of Minnesota

    Minneapolis, United States

    6 h-index

    10 publications

    1.3K citations

  3. Robert H. Lurie Comprehensive Cancer Center of Northwestern University

    Chicago, United States

    5 h-index

    5 publications

    315 citations

  4. Imperial College London

    London, United Kingdom

    5 h-index

    28 publications

    2.3K citations

  5. California Institute of Technology

    Pasadena, United States

    4 h-index

    13 publications

    2.4K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    11 publications

    1.2K citations

  7. California Polytechnic State University

    San Luis Obispo, United States

    3 h-index

    14 publications

    418 citations

  8. Broad Institute

    Cambridge, United States

    3 h-index

    14 publications

    1.5K citations

1–8 of 92

Venues

  1. ACS Synthetic Biology

    9 publications · 855 citations

    9

    h-index

  2. Frontiers in Bioengineering and Biotechnology

    3 publications · 72 citations

    3

    h-index

  3. Metabolic Engineering

    3 publications · 456 citations

    3

    h-index

  4. Synthetic Biology

    3 publications · 189 citations

    3

    h-index

  5. Biotechnology and Bioprocess Engineering

    2 publications · 38 citations

    2

    h-index

1–5