Concepedia

Cell Surface Complement Control

Cell Surface Complement Control is a regulatory mechanism that refers to the inhibition of complement activation on host cell surfaces through membrane-bound and glycosylphosphatidylinositol-anchored complement regulatory proteins, thereby preventing inadvertent immune-mediated damage to self-tissues.

37

Publications

2.5K

Citations

190

Authors

72

Institutions

Publications per year

2017–2026

1

Parents

Publications

37

Complement C3 convertase: Cell surface restriction of β1H control and generation of restriction on neuraminidase-treated cells

Michael K. Pangburn, Hans J. Müller‐Eberhard · Proceedings of the National Academy of Sciences · 1978 · 346 citations · Full text

, , +14

Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1.

Mohammed Saifuddin, Charles J. Parker, Mark E. Peeples et al. · The Journal of Experimental Medicine · 1995 · 246 citations · Full text

, , +16

Surface-associated heparin inhibits zymosan-induced activation of the human alternative complement pathway by augmenting the regulatory action of the control proteins on particle-bound C3b.

M Kazatchkine, D T Fearon, J E Silbert et al. · The Journal of Experimental Medicine · 1979 · 180 citations · Full text

, , +13

The Yeast<i>Candida albicans</i>Binds Complement Regulators Factor H and FHL-1

Taru Meri, Andrea Hartmann, D. Lenk et al. · Infection and Immunity · 2002 · 152 citations

, , +17

Critical Role of the C-Terminal Domains of Factor H in Regulating Complement Activation at Cell Surfaces

Viviana P. Ferreira, Andrew P. Herbert, Henry G. Hocking et al. · The Journal of Immunology · 2006 · 148 citations

, , +13

1–5 of 37

Authors

190

  1. MK
    Michael K. Pangburn

    The University of Texas Health Science Center at Tyler, United States

    4 publications · 614 citations

    4

    h-index

  2. VP
    Viviana P. Ferreira

    University of Toledo Medical Center, United States

    3 publications · 268 citations

    3

    h-index

  3. PF
    Peter F. Zipfel

    Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI), Germany

    3 publications · 351 citations

    3

    h-index

  4. SM
    Seppo Meri

    University of Helsinki, Finland

    2 publications · 178 citations

    2

    h-index

  5. SA
    Scott A. Rollins

    Alexion Pharmaceuticals (United States), United States

    2 publications · 155 citations

    2

    h-index

1–5 of 190

Institutions

72

  1. Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)

    Jena, Germany

    3 h-index

    15 publications

    1.8K citations

  2. The University of Texas Health Science Center at Tyler

    Tyler, United States

    3 h-index

    5 publications

    502 citations

  3. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    14 publications

    486 citations

  4. Washington University in St. Louis

    St Louis, United States

    2 h-index

    2 publications

    116 citations

  5. University of Helsinki

    Helsinki, Finland

    2 h-index

    4 publications

    356 citations

  6. Newcastle University

    Newcastle upon Tyne, United Kingdom

    2 h-index

    10 publications

    597 citations

  7. Inserm

    Paris, France

    2 h-index

    5 publications

    184 citations

  8. Lund University

    Lund, Sweden

    2 h-index

    3 publications

    126 citations

1–8 of 72

Venues

  1. The Journal of Immunology

    JI · 7 publications · 447 citations

    7

    h-index

  2. Blood

    4 publications · 264 citations

    4

    h-index

  3. Biomaterials

    3 publications · 165 citations

    3

    h-index

  4. Journal of Virology

    JVI · 3 publications · 150 citations

    3

    h-index

  5. Journal of Biological Chemistry

    JBC · 2 publications · 30 citations

    2

    h-index

1–5