Concepedia

Cell Line Immortalization

Cell Line Immortalization is a laboratory technique in cell biology that confers indefinite proliferative capacity to cultured animal cells by circumventing normal senescence and apoptosis mechanisms, thereby enabling the establishment of continuously dividing cell populations for research and biotechnological applications.

1.3K

Publications

82.9K

Citations

6.8K

Authors

1.5K

Institutions

Publications per year

2017–2026

135

Parents

Publications

1.3K

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

Frank L. Graham, W. C. Russell, James R. Smiley et al. · Journal of General Virology · 1977 · 4.9K citations

, , +16

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

Herbert D. Soule, J. Vázquez, Anna Long et al. · JNCI Journal of the National Cancer Institute · 1973 · 2.5K citations

, , +10

Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line

Babette Weksler, Eva-Anne Subileau, Nicolas Perrière et al. · The FASEB Journal · 2005 · 1.3K citations

, , +12

A Conditionally Immortalized Human Podocyte Cell Line Demonstrating Nephrin and Podocin Expression

Moin A. Saleem, Michael J. O’Hare, Jochen Reiser et al. · Journal of the American Society of Nephrology · 2002 · 1.1K citations

, , +16

E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

S N Boyer, David E. Wazer, Vimla Band · PubMed · 1996 · 931 citations

, , +17

1–5 of 1.3K

Authors

6.8K

  1. TK
    Tohru Kiyono

    Aichi Cancer Center, Japan

    13 publications · 320 citations

    12

    h-index

  2. OM
    Olivia M. Pereira‐Smith

    Baylor College of Medicine, United States

    11 publications · 1.4K citations

    11

    h-index

  3. TF
    Tomokazu Fukuda

    Tohoku University, Japan

    11 publications · 247 citations

    11

    h-index

  4. TE
    Takahiro Eitsuka

    Tohoku University, Japan

    9 publications · 212 citations

    9

    h-index

  5. JW
    Jerry W. Shay

    The University of Texas Southwestern Medical Center, United States

    7 publications · 911 citations

    7

    h-index

1–5 of 6.8K

Institutions

1.5K

  1. National Institutes of Health

    Bethesda, United States

    22 h-index

    96 publications

    7.3K citations

  2. Harvard University

    Cambridge, United States

    22 h-index

    70 publications

    4.6K citations

  3. National Cancer Institute

    Bethesda, United States

    21 h-index

    85 publications

    9K citations

  4. Inserm

    Paris, France

    20 h-index

    96 publications

    18.9K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    98 publications

    7.4K citations

  6. Cornell University

    Ithaca, United States

    16 h-index

    55 publications

    5K citations

  7. The University of Texas Southwestern Medical Center

    Dallas, United States

    15 h-index

    54 publications

    5.3K citations

  8. Karolinska Institutet

    Stockholm, Sweden

    15 h-index

    63 publications

    4.3K citations

1–8 of 1.5K

Venues

  1. PubMed

    Repository · 105 publications · 7.7K citations

    43

    h-index

  2. Journal of Virology

    JVI · 50 publications · 3.1K citations

    31

    h-index

  3. Molecular and Cellular Biology

    MCB · 39 publications · 3.6K citations

    28

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 33 publications · 4.5K citations

    27

    h-index

  5. International Journal of Cancer

    38 publications · 1.6K citations

    25

    h-index

1–5