Concepedia

Catalytic Promiscuity

Catalytic Promiscuity is the capacity of an enzyme to catalyze multiple, chemically distinct reactions under physiological conditions, distinguished from primary substrate specificity by its ability to accommodate alternative transition states and reaction mechanisms within the same active site.

380

Publications

19.6K

Citations

1.8K

Authors

541

Institutions

Publications per year

2017–2026

166

Parents

Publications

380

The 'evolvability' of promiscuous protein functions

Amir Aharoni, Leonid Gaidukov, Olga Khersonsky et al. · Nature Genetics · 2004 · 832 citations

, , +12

Catalytic Promiscuity in Biocatalysis: Using Old Enzymes to Form New Bonds and Follow New Pathways

Uwe T. Bornscheuer, Romas J. Kazlauskas · Angewandte Chemie International Edition · 2004 · 595 citations

, , +17

Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria

Daniel Sher, Libusha Kelly, Yanxiang Shi et al. · Proceedings of the National Academy of Sciences · 2010 · 285 citations · Full text

, , +17

Hyperstability and Substrate Promiscuity in Laboratory Resurrections of Precambrian β-Lactamases

Valeria A. Risso, Diego F. Mejia-Carmona, Eric A. Gaucher et al. · Journal of the American Chemical Society · 2013 · 262 citations · Full text

, , +17

International lending of last resort and moral hazard: a model of IMF's catalytic finance

Bernardo Guimarães, Giancarlo Corsetti, Nouriel Roubini · London School of Economics and Political Science Research Online (London School of Economics and Political Science) · 2006 · 247 citations

, , +17

1–5 of 380

Authors

1.8K

  1. FH
    Florian Hollfelder

    University of Cambridge, United Kingdom

    7 publications · 377 citations

    7

    h-index

  2. SL
    Shu‐Ming Li

    Philipps University of Marburg, Germany

    6 publications · 159 citations

    6

    h-index

  3. ZG
    Zhi Guan

    Southwest University, China

    6 publications · 292 citations

    6

    h-index

  4. HT
    Hernán Terenzi

    Universidade Federal de Santa Catarina, Brazil

    6 publications · 432 citations

    6

    h-index

  5. AN
    Ademir Neves

    Universidade Federal de Santa Catarina, Brazil

    6 publications · 432 citations

    6

    h-index

1–5 of 1.8K

Institutions

541

  1. Chinese Academy of Sciences

    Beijing, China

    13 h-index

    69 publications

    2K citations

  2. University of Groningen

    Groningen, The Netherlands

    11 h-index

    46 publications

    2.6K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    10 h-index

    38 publications

    1.9K citations

  4. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    10 h-index

    68 publications

    4K citations

  5. University of Graz

    Graz, Austria

    9 h-index

    30 publications

    1.5K citations

  6. University of Illinois Urbana-Champaign

    Urbana, United States

    9 h-index

    39 publications

    3.8K citations

  7. Uppsala University

    Uppsala, Sweden

    8 h-index

    21 publications

    913 citations

  8. University of Chinese Academy of Sciences

    Beijing, China

    8 h-index

    17 publications

    604 citations

1–8 of 541

Venues

  1. ChemBioChem

    26 publications · 1.1K citations

    20

    h-index

  2. Journal of the American Chemical Society

    JACS · 22 publications · 1.9K citations

    20

    h-index

  3. ACS Catalysis

    21 publications · 810 citations

    18

    h-index

  4. Biochemistry

    22 publications · 1.1K citations

    17

    h-index

  5. Angewandte Chemie International Edition

    18 publications · 1.6K citations

    17

    h-index

1–5