Concepedia

Cascade Release Design

Cascade Release Design is a double prodrug strategy that belongs to the class of drug delivery systems, distinguished by its sequential, self-immolative activation mechanism enabling the timed release of two therapeutic agents through a single administration event.

3

Publications

164

Citations

22

Authors

7

Institutions

Publications per year

2017–2026

3

Parents

Publications

3

Cascade Drug-Release Strategy for Enhanced Anticancer Therapy

Xu Zhang, Sheng Wang, Guohui Cheng et al. · Matter · 2021 · 65 citations · Full text

, , +14

Click, Release, and Fluoresce: A Chemical Strategy for a Cascade Prodrug System for Codelivery of Carbon Monoxide, a Drug Payload, and a Fluorescent Reporter

Ladie Kimberly C. De La Cruz, Stéphane L. Benoit, Zhixiang Pan et al. · Organic Letters · 2018 · 57 citations

, , +17

Self-preparation system using glucose oxidase-inspired nitroreductase amplification for cascade-responsive drug release and multidrug resistance reversion

Fangying Yu, Xuwei Shang, Yun Zhu et al. · Biomaterials · 2021 · 42 citations

, , +16

Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma

Zhihao Guo, Linyun Xiu, Yumei Li et al. · Journal of Controlled Release · 2024 · 17 citations

, , +16

1–4 of 3

Authors

22

  1. BY
    Bingchen Yu

    Georgia State University, United States

    1 publications · 57 citations

    1

    h-index

  2. XJ
    Xingyue Ji

    Georgia State University, United States

    1 publications · 57 citations

    1

    h-index

  3. JC
    Jin Chang

    Tianjin University, China

    1 publications · 65 citations

    1

    h-index

  4. FH
    Fuqiang Hu

    Zhejiang University, China

    1 publications · 42 citations

    1

    h-index

  5. ZP
    Zhixiang Pan

    Georgia State University, United States

    1 publications · 57 citations

    1

    h-index

1–5 of 22

Institutions

7

  1. Sir Run Run Shaw Hospital

    Hangzhou, China

    1 h-index

    1 publications

    42 citations

  2. Zhejiang University

    Hangzhou, China

    1 h-index

    8 publications

    336 citations

  3. National University of Singapore

    Singapore, Singapore

    1 h-index

    1 publications

    65 citations

  4. Tianjin University

    Tianjin, China

    1 h-index

    5 publications

    325 citations

  5. University of Georgia

    Athens, United States

    1 h-index

    2 publications

    114 citations

  6. Nanjing Drum Tower Hospital

    Nanjing, China

    1 h-index

    1 publications

    42 citations

  7. Georgia State University

    Atlanta, United States

    1 h-index

    5 publications

    285 citations

  8. Wenzhou Medical University

    Wenzhou, China

    1 publications

    17 citations

1–8 of 7

Venues

  1. Matter

    1 publications · 65 citations

    1

    h-index

  2. Biomaterials

    1 publications · 42 citations

    1

    h-index

  3. Organic Letters

    OL · 1 publications · 57 citations

    1

    h-index

  4. Journal of Controlled Release

    1 publications · 17 citations

1–4