Concepedia

Carcinogenicity Extrapolation

Carcinogenicity Extrapolation is a regulatory toxicological method that uses empirical data and mechanistic models derived from high-dose animal studies or in vitro systems to predict the likelihood and magnitude of cancer risk in humans under lower-dose or environmentally relevant exposure conditions.

76

Publications

3.5K

Citations

173

Authors

68

Institutions

Publications per year

2017–2026

1

Parents

Publications

76

Multivariate Environmental Statistics.

George A. F. Seber, G. P. Patil, C. R. Rao · Biometrics · 1995 · 349 citations

, , +13

“Safety” Testing of Carcinogenic Agents

Nathan Mantel, W. Ray Bryan · JNCI Journal of the National Cancer Institute · 1961 · 235 citations

, , +15

Quantitative Risk Assessment

John Van Ryzin · Journal of Occupational and Environmental Medicine · 1980 · 203 citations

, , +14

Interspecies comparison of carcinogenic potency

Edmund A. C. Crouch, Richard E. Wilson · Journal of Toxicology and Environmental Health · 1979 · 152 citations

, , +14

Interspecies extrapolation in carcinogenesis: prediction between rats and mice.

L S Gold, Leslie Bernstein, Renae Magaw et al. · Environmental Health Perspectives · 1989 · 123 citations · Full text

, , +11

1–5 of 76

Authors

173

  1. DW
    David W. Gaylor

    National Center for Toxicological Research, United States

    6 publications · 157 citations

    6

    h-index

  2. KS
    Kenny S. Crump

    Louisiana Tech University, United States

    4 publications · 165 citations

    4

    h-index

  3. RL
    Ralph L. Kodell

    National Center for Toxicological Research, United States

    4 publications · 86 citations

    4

    h-index

  4. TH
    Thomas H. Slone

    Lawrence Berkeley National Laboratory, United States

    3 publications · 169 citations

    3

    h-index

  5. JB
    Jarrod Bailey

    Newcastle University, United Kingdom

    3 publications · 81 citations

    3

    h-index

1–5 of 173

Institutions

68

  1. National Institute of Environmental Health Sciences

    Durham, United States

    6 h-index

    12 publications

    446 citations

  2. National Institutes of Health

    Bethesda, United States

    6 h-index

    8 publications

    308 citations

  3. National Center for Toxicological Research

    Pine Bluff, United States

    5 h-index

    14 publications

    325 citations

  4. United States Food and Drug Administration

    Silver Spring, United States

    5 h-index

    14 publications

    315 citations

  5. Harvard University

    Cambridge, United States

    5 h-index

    9 publications

    507 citations

  6. Lawrence Berkeley National Laboratory

    Berkeley, United States

    4 h-index

    11 publications

    655 citations

  7. Environmental Protection Agency

    Washington, United States

    3 h-index

    11 publications

    178 citations

  8. Physicians Committee for Responsible Medicine

    Washington, United States

    2 h-index

    2 publications

    69 citations

1–8 of 68

Venues

  1. Environmental Health Perspectives

    EHP · 15 publications · 574 citations

    14

    h-index

  2. Risk Analysis

    11 publications · 256 citations

    11

    h-index

  3. PubMed

    Repository · 11 publications · 613 citations

    11

    h-index

  4. Regulatory Toxicology and Pharmacology

    RTP · 3 publications · 96 citations

    3

    h-index

  5. Human & Experimental Toxicology

    3 publications · 54 citations

    3

    h-index

1–5