Concepedia

Brachyury Function

Brachyury Function is a molecular genetic mechanism defined as a transcriptional regulator within the T-box family of genes that directs mesodermal cell fate specification and axial development during vertebrate embryogenesis.

230

Publications

24.8K

Citations

944

Authors

346

Institutions

Publications per year

2017–2026

31

Parents

Publications

230

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

James C. Smith, Brenda M. J. Price, Jeremy Green et al. · Cell · 1991 · 970 citations

, , +10

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

Newbury-Ecob Ra, David I. Wilson, Andrew R.J. Curtis et al. · Nature Genetics · 1997 · 929 citations

, , +8

Development of definitive endoderm from embryonic stem cells in culture

Atsushi Kubo, Katsunori Shinozaki, John M. Shannon et al. · Development · 2004 · 836 citations

, , +17

<i>Xwnt11</i>is a target of<i>Xenopus</i>Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway

Masazumi Tada, James C. Smith · Development · 2000 · 680 citations

, , +17

Expression of the T-box family genes,Tbx1-Tbx5, during early mouse development

Deborah L. Chapman, Nancy Garvey, Sarah Hancock et al. · Developmental Dynamics · 1996 · 660 citations

, , +17

1–5 of 230

Authors

944

  1. JC
    James C. Smith

    University of Cambridge, United Kingdom

    16 publications · 3.9K citations

    16

    h-index

  2. BG
    Bernhard G. Herrmann

    Max Planck Institute for Molecular Genetics, Germany

    16 publications · 3.6K citations

    15

    h-index

  3. CP
    Claudia Palena

    National Cancer Institute, United States

    10 publications · 1.2K citations

    10

    h-index

  4. AK
    Andreas Kispert

    Medizinische Hochschule Hannover, Germany

    9 publications · 2.1K citations

    9

    h-index

  5. DH
    Duane H. Hamilton

    National Cancer Institute, United States

    9 publications · 1.1K citations

    9

    h-index

1–5 of 944

Institutions

346

  1. Kyoto University

    Kyoto, Japan

    16 h-index

    43 publications

    5K citations

  2. National Cancer Institute

    Bethesda, United States

    14 h-index

    72 publications

    9.4K citations

  3. Center for Cancer Research

    Bethesda, United States

    13 h-index

    60 publications

    6.6K citations

  4. Max Planck Institute for Developmental Biology

    Tübingen, Germany

    12 h-index

    28 publications

    9K citations

  5. Max Planck Society

    Munich, Germany

    11 h-index

    26 publications

    6.7K citations

  6. National Institutes of Health

    Bethesda, United States

    8 h-index

    42 publications

    4.6K citations

  7. Cornell University

    Ithaca, United States

    8 h-index

    34 publications

    1.6K citations

  8. University of Washington

    Seattle, United States

    8 h-index

    24 publications

    2.1K citations

1–8 of 346

Venues

  1. Development

    46 publications · 7.2K citations

    37

    h-index

  2. Developmental Biology

    20 publications · 2.1K citations

    19

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 825 citations

    8

    h-index

  4. Developmental Dynamics

    8 publications · 1.1K citations

    8

    h-index

  5. Genes & Development

    7 publications · 1.3K citations

    7

    h-index

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