Concepedia

Bottom-up Sequencing

Bottom-Up Sequencing is a de novo peptide sequencing strategy that belongs to the class of mass spectrometry-based sequencing approaches, distinguished by its reconstruction of peptide sequences starting from experimentally observed fragment ions and incrementally assembling them into full sequences without reliance on genomic or proteomic databases.

77

Publications

5.3K

Citations

373

Authors

132

Institutions

Publications per year

2017–2026

20

Parents

Publications

77

Online Parallel Accumulation–Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer

Florian Meier, Andreas‐David Brunner, Scarlet Koch et al. · Molecular & Cellular Proteomics · 2018 · 1K citations · Full text

, , +15

Protein Ladder Sequencing

Brian T. Chait, Rong Wang, Ronald C. Beavis et al. · Science · 1993 · 311 citations

, , +13

A Dynamic Programming Approach to De Novo Peptide Sequencing via Tandem Mass Spectrometry

Ting Chen, Ming‐Yang Kao, Matthew Tepel et al. · Journal of Computational Biology · 2001 · 250 citations

, , +14

De novo peptide sequencing and quantitative profiling of complex protein mixtures using mass-coded abundance tagging

Gerard Cagney, Andrew Emili · Nature Biotechnology · 2002 · 231 citations

, , +15

Expanding the detectable HLA peptide repertoire using electron-transfer/higher-energy collision dissociation (EThcD)

Geert P. M. Mommen, Christian K. Frese, Hugo D. Meiring et al. · Proceedings of the National Academy of Sciences · 2014 · 188 citations · Full text

, , +16

1–5 of 77

Authors

373

  1. KV
    Kira Vyatkina

    Saint Petersburg Academic University, Russia

    4 publications · 127 citations

    4

    h-index

  2. TM
    Theo M. Luider

    Erasmus MC, Netherlands

    3 publications · 102 citations

    3

    h-index

  3. MM
    Martijn M. VanDuijn

    Erasmus MC, Netherlands

    3 publications · 102 citations

    3

    h-index

  4. SW
    Si Wu

    Pacific Northwest National Laboratory, United States

    3 publications · 102 citations

    3

    h-index

  5. XL
    Xiaowen Liu

    Indiana University – Purdue University Indianapolis, United States

    3 publications · 102 citations

    3

    h-index

1–5 of 373

Institutions

132

  1. Bruker (Germany)

    Karlsruhe, Germany

    4 h-index

    26 publications

    9.5K citations

  2. Bruker (United States)

    Billerica, United States

    4 h-index

    5 publications

    1.2K citations

  3. Saint Petersburg Academic University

    Saint Petersburg, Russia

    4 h-index

    6 publications

    269 citations

  4. Fahrenheit (Germany)

    Munich, Germany

    3 h-index

    23 publications

    9.4K citations

  5. Pacific Northwest National Laboratory

    Richland, United States

    3 h-index

    7 publications

    275 citations

  6. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    3 h-index

    4 publications

    173 citations

  7. University of Liège

    Liège, Belgium

    3 h-index

    18 publications

    1.1K citations

  8. Environmental Molecular Sciences Laboratory

    Richland, United States

    3 h-index

    7 publications

    275 citations

1–8 of 132

Venues

  1. Analytical Chemistry

    7 publications · 345 citations

    7

    h-index

  2. Journal of the American Society for Mass Spectrometry

    JASMS · 7 publications · 518 citations

    7

    h-index

  3. Journal of Proteome Research

    JPR · 6 publications · 260 citations

    6

    h-index

  4. Analytical Biochemistry

    4 publications · 217 citations

    4

    h-index

  5. FEBS Letters

    3 publications · 84 citations

    3

    h-index

1–5