Concepedia

Biosensor-guided Regulation

Biosensor-Guided Regulation is a regulatory control strategy in synthetic biology that uses intracellular biosensors to dynamically modulate gene expression in response to specific metabolites or environmental signals, enabling real-time feedback control of metabolic pathways.

20

Publications

933

Citations

117

Authors

38

Institutions

Publications per year

2017–2026

14

Parents

Publications

20

Design of a programmable biosensor-CRISPRi genetic circuits for dynamic and autonomous dual-control of metabolic flux in Bacillus subtilis

Yaokang Wu, Taichi Chen, Yanfeng Liu et al. · Nucleic Acids Research · 2019 · 176 citations · Full text

, , +17

Tuning the Binding Affinity of Heme-Responsive Biosensor for Precise and Dynamic Pathway Regulation

Jian Zhang, Zhiguo Wang, Tianyuan Su et al. · iScience · 2020 · 80 citations · Full text

, , +16

SensiPath: computer-aided design of sensing-enabling metabolic pathways

Baudoin Delépine, Vincent Libis, Pablo Carbonell et al. · Nucleic Acids Research · 2016 · 76 citations · Full text

, , +15

Biosensor-assisted transcriptional regulator engineering for Methylobacterium extorquens AM1 to improve mevalonate synthesis by increasing the acetyl-CoA supply

Wei‐Fan Liang, Lanyu Cui, Jinyu Cui et al. · Metabolic Engineering · 2016 · 73 citations

, , +16

Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators

Javier F. Juárez, Begoña Lecube-Azpeitia, Stuart L. Brown et al. · Nature Communications · 2018 · 66 citations · Full text

, , +17

1–5 of 20

Authors

117

  1. ST
    Shuyu Tan

    State Key Laboratory of Food Science and Technology, China

    2 publications · 53 citations

    2

    h-index

  2. HL
    Haiyan Liu

    University of Florida, United States

    2 publications · 53 citations

    2

    h-index

  3. FS
    Feng Shi

    Jiangnan University, China

    2 publications · 53 citations

    2

    h-index

  4. YL
    Yongfu Li

    Jiangnan University, China

    2 publications · 53 citations

    2

    h-index

  5. JC
    Jinyu Cui

    Tianjin University, China

    1 publications · 73 citations

    1

    h-index

1–5 of 117

Institutions

38

  1. Jiangnan University

    Wuxi, China

    4 h-index

    26 publications

    2K citations

  2. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    18 publications

    403 citations

  3. State Key Laboratory of Food Science and Technology

    Wuxi, China

    2 h-index

    11 publications

    304 citations

  4. Tianjin University of Science and Technology

    Tianjin, China

    1 h-index

    2 publications

    38 citations

  5. Temple University

    Philadelphia, United States

    1 h-index

    1 publications

    54 citations

  6. Ghent University Hospital

    Ghent, Belgium

    1 h-index

    6 publications

    228 citations

  7. Qingdao Institute of Bioenergy and Bioprocess Technology

    Qingdao, China

    1 h-index

    1 publications

    80 citations

  8. University of Chicago

    Chicago, United States

    1 h-index

    3 publications

    105 citations

1–8 of 38

Venues

  1. ACS Synthetic Biology

    2 publications · 86 citations

    2

    h-index

  2. Applied Microbiology and Biotechnology

    2 publications · 68 citations

    2

    h-index

  3. Microbial Cell Factories

    2 publications · 65 citations

    2

    h-index

  4. Biosensors and Bioelectronics

    2 publications · 49 citations

    2

    h-index

  5. Nucleic Acids Research

    2 publications · 252 citations

    2

    h-index

1–5