Concepedia

Biomarker-guided Combinations

Biomarker-Guided Combinations is a therapeutic strategy in combination cancer therapy that involves the selection of drug combinations based on specific molecular or cellular biomarkers predictive of treatment response, thereby enabling personalized and targeted intervention.

22

Publications

1.3K

Citations

297

Authors

162

Institutions

Publications per year

2017–2026

13

Parents

Publications

22

Effective drug combinations in breast, colon and pancreatic cancer cells

Patricia Jaaks, Elizabeth A. Coker, Daniël J. Vis et al. · Nature · 2022 · 463 citations · Full text

, , +14

Individualized prognosis of cognitive decline and dementia in mild cognitive impairment based on plasma biomarker combinations

Nicholas Cullen, Antoine Leuzy, Sebastian Palmqvist et al. · Nature Aging · 2020 · 192 citations

, , +16

Alzheimer's disease biomarker‐guided diagnostic workflow using the added value of six combined cerebrospinal fluid candidates: Aβ<sub>1–42</sub>, total‐tau, phosphorylated‐tau, NFL, neurogranin, and YKL‐40

Harald Hampel, Nicola Toschi, Filippo Baldacci et al. · Alzheimer s & Dementia · 2018 · 140 citations

, , +17

An adaptive, biomarker-directed platform study of durvalumab in combination with targeted therapies in advanced urothelial cancer

Thomas Powles, Danielle Carroll, Simon Chowdhury et al. · Nature Medicine · 2021 · 116 citations

, , +15

Biomarker-directed, pembrolizumab-based combination therapy in non-small cell lung cancer: phase 2 KEYNOTE-495/KeyImPaCT trial interim results

Martin Gutierrez, Wei‐Sen Lam, Matthew D. Hellmann et al. · Nature Medicine · 2023 · 45 citations

, , +16

1–5 of 22

Authors

297

  1. KB
    Kaj Blennow

    University of Gothenburg, Sweden

    2 publications · 332 citations

    2

    h-index

  2. JC
    Joan Carles

    Vall d'Hebron Hospital Universitari, Spain

    2 publications · 148 citations

    2

    h-index

  3. JC
    Jan Cosaert

    Eli Lilly (United States), United States

    2 publications · 148 citations

    2

    h-index

  4. AR
    Alain Ravaud

    Hôpital Saint-André, France

    2 publications · 148 citations

    2

    h-index

  5. GG
    Gwénaëlle Gravis

    Institut Paoli-Calmettes, France

    2 publications · 148 citations

    2

    h-index

1–5 of 297

Institutions

162

  1. Harvard University

    Cambridge, United States

    3 h-index

    4 publications

    637 citations

  2. University of Washington

    Seattle, United States

    3 h-index

    3 publications

    158 citations

  3. Vall d'Hebron Hospital Universitari

    Barcelona, Spain

    3 h-index

    3 publications

    193 citations

  4. University College London

    London, United Kingdom

    2 h-index

    2 publications

    332 citations

  5. Icahn School of Medicine at Mount Sinai

    New York, United States

    2 h-index

    2 publications

    148 citations

  6. Center for Systems Biology

    Boston, United States

    2 h-index

    4 publications

    74 citations

  7. Fred Hutch Cancer Center

    Seattle, United States

    2 h-index

    2 publications

    38 citations

  8. Beatson West of Scotland Cancer Centre

    Glasgow, United Kingdom

    2 h-index

    2 publications

    148 citations

1–8 of 162

Venues

  1. Nature Medicine

    2 publications · 161 citations

    2

    h-index

  2. BMC Cancer

    2 publications · 58 citations

    2

    h-index

  3. Annals of Oncology

    1 publications · 32 citations

    1

    h-index

  4. Journal of Thoracic Oncology

    1 publications · 25 citations

    1

    h-index

  5. Cancer Research

    1 publications · 17 citations

    1

    h-index

1–5