Concepedia

Biomarker Threshold Optimization

Biomarker Threshold Optimization is a methodological framework in precision medicine that determines the optimal cutoff value for a biomarker to guide therapeutic decisions by balancing clinical sensitivity, specificity, and treatment outcomes.

13

Publications

1.7K

Citations

71

Authors

30

Institutions

Publications per year

2017–2026

8

Parents

Publications

13

Optimal Cut-point and Its Corresponding Youden Index to Discriminate Individuals Using Pooled Blood Samples

Enrique F. Schisterman, Neil J. Perkins, Aiyi Liu et al. · Epidemiology · 2004 · 1.2K citations

, , +14

Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers

Gemma Salvadó, José Luís Molinuevo, Anna Brugulat‐Serrat et al. · Alzheimer s Research & Therapy · 2019 · 205 citations · Full text

, , +17

Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients

Guoqiang Yuan, Liang Niu, Yinian Zhang et al. · Journal of Neuro-Oncology · 2017 · 49 citations

, , +17

Finding the optimal cut-point for Gaussian and Gamma distributed biomarkers

Matteo Rota, Laura Antolini · Computational Statistics & Data Analysis · 2013 · 47 citations · Full text

, , +9

Determination of cutoff values for biomarkers in clinical studies

Sook‐Young Woo, Seonwoo Kim · Precision and Future Medicine · 2020 · 46 citations · Full text

, , +13

1–5 of 13

Authors

71

  1. MÁ
    Miguel Á. Vega-Rodríguez

    Universidad de Extremadura, Spain

    1 publications · 18 citations

    1

    h-index

  2. HY
    Han Yu

    Roswell Park Comprehensive Cancer Center, United States

    1 publications · 14 citations

    1

    h-index

  3. MH
    Man‐Jen Hsu

    Institute of Statistical Science, Academia Sinica, Taiwan

    1 publications · 23 citations

    1

    h-index

  4. SW
    Sook‐Young Woo

    Sungkyunkwan University, South Korea

    1 publications · 46 citations

    1

    h-index

  5. HM
    Howard Mackey

    Johns Hopkins University, United States

    1 publications · 19 citations

    1

    h-index

1–5 of 71

Institutions

30

  1. Lanzhou University

    Lanzhou, China

    1 h-index

    9 publications

    441 citations

  2. UK Dementia Research Institute

    London, United Kingdom

    1 h-index

    1 publications

    205 citations

  3. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine

    Madrid, Spain

    1 h-index

    4 publications

    820 citations

  4. National Hospital for Neurology and Neurosurgery

    London, United Kingdom

    1 h-index

    1 publications

    205 citations

  5. University of Göttingen

    Göttingen, Germany

    1 h-index

    2 publications

    60 citations

  6. MRC Biostatistics Unit

    Cambridge, United Kingdom

    1 h-index

    2 publications

    46 citations

  7. Barcelonaβeta Brain Research Center

    Barcelona, Spain

    1 h-index

    9 publications

    1.8K citations

  8. University of Gothenburg

    Gothenburg, Sweden

    1 h-index

    2 publications

    410 citations

1–8 of 30

Venues

  1. Statistical Methods in Medical Research

    1 publications · 30 citations

    1

    h-index

  2. Epidemiology

    1 publications · 1.2K citations

    1

    h-index

  3. Journal of Neuro-Oncology

    1 publications · 49 citations

    1

    h-index

  4. Oral Oncology

    1 publications · 14 citations

    1

    h-index

  5. Contemporary Clinical Trials

    1 publications · 19 citations

    1

    h-index

1–5