Concepedia

Bioassay-guided Fractionation

Bioassay-Guided Fractionation is a systematic isolation method used in natural product drug discovery that employs biological activity testing at each separation step to identify and purify bioactive compounds from complex mixtures, particularly in marine and plant-derived extracts.

1.6K

Publications

75.2K

Citations

7.9K

Authors

1.7K

Institutions

Publications per year

2017–2026

357

Parents

Publications

1.6K

Ajoene, a Sulfur-Rich Molecule from Garlic, Inhibits Genes Controlled by Quorum Sensing

Tim Holm Jakobsen, Maria van Gennip, Richard K. Phipps et al. · Antimicrobial Agents and Chemotherapy · 2012 · 455 citations · Full text

, , +17

Bioactivity-Based Molecular Networking for the Discovery of Drug Leads in Natural Product Bioassay-Guided Fractionation

Louis‐Félix Nothias, Mélissa Nothias-Esposito, Ricardo Silva et al. · Journal of Natural Products · 2018 · 406 citations · Full text

, , +17

Antibacterial activities of the extracts, fractions and isolated compounds from Canarium patentinervium Miq. against bacterial clinical isolates

Achyut Adhikari, Christophe Wiart · BMC Complementary Medicine and Therapies · 2020 · 374 citations · Full text

, , +17

Flavonoids from Hypericum perforatum Show Antidepressant Activity in the Forced Swimming Test

Veronika Butterweck, Guido Jürgenliemk, Adolf Nahrstedt et al. · Planta Medica · 2000 · 364 citations

, , +11

Identification of a Potent Phytoestrogen in Hops (Humulus lupulus L.) and Beer

S. R. Milligan, J Kalita, Arne Heyerick et al. · The Journal of Clinical Endocrinology & Metabolism · 1999 · 351 citations

, , +14

1–5 of 1.6K

Authors

7.9K

  1. AD
    A. Douglas Kinghorn

    University of Illinois Chicago, United States

    28 publications · 1.5K citations

    23

    h-index

  2. HM
    Hisashi Matsuda

    Kyoto Pharmaceutical University, Japan

    18 publications · 1.4K citations

    17

    h-index

  3. JM
    John M. Pezzuto

    University of Illinois Chicago, United States

    18 publications · 1.2K citations

    16

    h-index

  4. ZL
    Zhi Long Liu

    China Agricultural University, China

    15 publications · 647 citations

    13

    h-index

  5. NR
    Norman R. Farnsworth

    University of Illinois Chicago, United States

    13 publications · 737 citations

    13

    h-index

1–5 of 7.9K

Institutions

1.7K

  1. University of Illinois Chicago

    Chicago, United States

    33 h-index

    307 publications

    16.9K citations

  2. University of Mississippi

    Oxford, United States

    25 h-index

    179 publications

    9.2K citations

  3. Chinese Academy of Sciences

    Beijing, China

    24 h-index

    141 publications

    6.3K citations

  4. China Agricultural University

    Beijing, China

    21 h-index

    97 publications

    4.8K citations

  5. Seoul National University

    Seoul, South Korea

    21 h-index

    82 publications

    4.7K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    20 h-index

    149 publications

    8.8K citations

  7. Kyoto Pharmaceutical University

    Kyoto, Japan

    20 h-index

    89 publications

    6K citations

  8. Korea Research Institute of Chemical Technology

    Daejeon, South Korea

    19 h-index

    101 publications

    4.5K citations

1–8 of 1.7K

Venues

  1. Journal of Natural Products

    276 publications · 15.6K citations

    70

    h-index

  2. Planta Medica

    115 publications · 6.1K citations

    47

    h-index

  3. Journal of Agricultural and Food Chemistry

    77 publications · 4.2K citations

    45

    h-index

  4. Molecules

    72 publications · 2.4K citations

    33

    h-index

  5. Chemical and Pharmaceutical Bulletin

    43 publications · 2.3K citations

    30

    h-index

1–5